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首页> 外文期刊>European journal of clinical nutrition >Comparing single-frequency bioelectrical impedance analysis against deuterium dilution to assess total body water
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Comparing single-frequency bioelectrical impedance analysis against deuterium dilution to assess total body water

机译：比较单频生物电阻抗分析与氘稀释以评估人体总水

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Background/Objectives:In this study, we aimed to validate the accuracy of single-frequency bioelectrical impedance analysis (SF-BIA) at 50 kHz to assess total body water (TBW) against the reference technique deuterium dilution (D 2 O) and to explore if the simple clinical parameters extracellular fluid (ECF) composition and body shape explain individual differences between D 2 O and SF-BIA (Diff BIA-D 2 O).Subjects/Methods:We assessed TBW with D 2 O and SF-BIA in 26 women and 26 men without known disease or anomalous body shapes. In addition, we measured body shape with anthropometry and ECF composition (osmolality, albumin, glucose, urea, creatinine, sodium and potassium).Results: On group average, SF-BIA to predict TBW agreed well with D 2 O (SF-BIA, 39.810.1 l; D 2 O, 40.410.2 l; and Diff BIA-D 2 O 0.7 l). In four individuals (outliers; 15% of the study population), Diff BIA-D 2 O was high (6.8 to 3.8 l). Diff BIA-D 2 O was associated with individual variations in body shape rather than ECF composition. Using gender-specific analysis, we found that individual variability of waist circumference in men and arm length in women significantly contributed to Diff BIA-D 2 O. When removing the four outliers, these associations were lost.Conclusions:In the majority of our sample, BIA agreed well with D 2 O. Adjusting for individual variability in body shape by anthropometrical assessment could possibly improve the accuracy of SF-BIA for individuals who deviate from mean values with respect to body shape. However, further studies with higher subject numbers are needed to confirm our findings.
机译：背景/目的：在这项研究中，我们旨在验证单频生物电阻抗（SF-BIA）在50 kHz时的准确性，以评估参考水氘稀释（D 2 O）对人体总水（TBW）的影响，并针对探索简单的临床参数细胞外液（ECF）组成和体型是否能解释D 2 O和SF-BIA（Diff BIA-D 2 O）之间的个体差异。研究对象/方法：我们用D 2 O和SF-BIA评估了TBW没有已知疾病或异常体型的26位女性和26位男性中。此外，我们通过人体测量法和ECF组成（渗透压，白蛋白，葡萄糖，尿素，肌酐，钠和钾）测量了身体形态。 ; 39.810.1 l; D 2 O，40.410.2 l;和Diff BIA-D 2 O 0.7 l）。在四个个体（异常值;占研究人群的15％）中，Diff BIA-D 2 O高（6.8至3.8 l）。 Diff BIA-D 2 O与个体形状的个体变化而不是ECF组成有关。使用针对性别的分析，我们发现男性腰围和女性臂长的个体差异显着影响了Diff BIA-D 2 O.当除去四个异常值时，这些关联消失了。结论：在我们的大多数样本中，BIA与D 2 O非常吻合。通过人体测量评估调整个人体形的变异性可能会提高SF-BIA对于偏离体形平均值的个人的准确性。但是，需要进一步的研究以更高的主题数来证实我们的发现。

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