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首页> 外文期刊>European journal of paediatric neurology: EJPN : official journal of the European Paediatric Neurology Society >Epileptic encephalopathy with bilateral continuous spike-waves during slow sleep in a child with vacuolating megalencephalic leukoencephalopathy.
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Epileptic encephalopathy with bilateral continuous spike-waves during slow sleep in a child with vacuolating megalencephalic leukoencephalopathy.

机译：患有空泡性大脑白质脑病的儿童在缓慢睡眠期间出现双侧连续尖峰波的癫痫性脑病。

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摘要

This case report describes the clinical evolution of a symptomatic epileptic encephalopathy with bilateral continuous spike-waves during slow wave sleep (BCSWS) in a 3-year-old girl. Her epilepsy with focal motor seizures during sleep was later complicated by myoclonic, atonic and clonic seizures culminating in BCSWS. The clinical picture, clinical course and magnetic resonance imaging findings were characterstic of primary white matter disease, probably, vacuolated megalencephalic leukoencephalopathy with subcortical cysts (MLC). To the best of our knowledge, this is the first reported case of BSCWS in a patient with leukodystrophies or MLC. This case report indicates that epileptic encephalopathy with BSCWS may be a cause of neurological or neuropsychological deterioration in MLC.
机译：该病例报告描述了一名3岁女孩在慢波睡眠（BCSWS）期间伴有双侧连续尖峰波的症状性癫痫性脑病的临床演变。后来她的癫痫​​发作伴有局灶性运动性癫痫发作，后来又因BCSWS导致肌阵挛，无力和阵挛性癫痫发作而并发。临床表现，临床过程和磁共振成像表现是原发性白质病的特征，可能是空化的巨脑白质脑病伴皮质下囊肿（MLC）。据我们所知，这是白细胞营养不良或MLC患者中首例报告的BSCWS病例。该病例报告表明，伴有BSCWS的癫痫性脑病可能是MLC神经或神经心理恶化的原因。

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