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首页> 外文期刊>European journal of paediatric neurology: EJPN : official journal of the European Paediatric Neurology Society >10-Year outcome of childhood epilepsy in well-functioning children and adolescents.
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10-Year outcome of childhood epilepsy in well-functioning children and adolescents.

机译：运作良好的儿童和青少年的儿童癫痫病10年结局。

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摘要

BACKGROUND: A population based study of epilepsy in children from a Swedish county including all children aged 1 month to 16 years was reported in 2006. AIM: To describe the medical outcome, seizure types, epilepsy syndromes, treatment, individual and family history in children from this study who were well-functioning in January 1997 and the outcome after 10 years. METHODS: Forty-five individuals, 11-21 years, 19 females, and their parents responded to a questionnaire and the hospital records were reviewed. RESULTS: At the end of the 10-year period 75.6% of the patients were in remission. Focal seizures and focal seizures with secondary generalization were found in 57.8%. Rolandic epilepsy had been diagnosed in 33.3%, other idiopathic focal epilepsies in 11.0%, cryptogenic and symptomatic focal epilepsies in 22.2%, childhood absence epilepsy in 8.9%, juvenile absence epilepsy and Jeavons syndrome in each 2.2%, West syndrome in 4.4%, and other "generalized" epilepsies in 15.5%. The patients had a history of simple febrile seizures in 15.6% and of primary headache in 24.4%. Monotherapy with antiepileptic drugs was used by 64.4%, and valproate was the most common first drug of choice. A family history of epilepsy was found in 44.4%, febrile seizures in 17.7%, and primary headache in 57.8%. A coincidence of focal and generalized epilepsy phenotypes was found in some families. CONCLUSIONS: Longitudinal studies are of importance in epilepsy epidemiology. Our results reflect the selection of only well-functioning individuals with epilepsy from the population based original study.
机译：背景：2006年，瑞典对包括所有1个月至16岁的所有儿童在内的瑞典儿童进行了一项基于人群的癫痫研究。目的：描述儿童的医疗结局，癫痫发作类型，癫痫综合征，治疗方法，个人和家族史这项研究得出的结论是，他们在1997年1月运作良好，并在10年后取得了成果。方法：45名11至21岁的女性，19名女性及其父母对问卷进行了回应，并回顾了医院的病历。结果：在10年期结束时，有75.6％的患者缓解了。局灶性癫痫和继发性泛发性局灶性癫痫占57.8％。诊断为罗兰性癫痫的比例为33.3％，其他特发性局灶性癫痫的比例为11.0％，隐源性和有症状的局灶性癫痫的比例为22.2％，儿童失神癫痫的比例为8.9％，青少年失神癫痫和Jeavons综合征的比例为2.2％，西综合征的比例为4.4％，和其他“一般性”癫痫病患者占15.5％。这些患者有单纯性高热惊厥史，占15.6％，原发性头痛，占24.4％。抗癫痫药物的单一疗法使用率为64.4％，丙戊酸是最常见的首选药物。有癫痫家族史的占44.4％，高热惊厥的占17.7％，原发性头痛的占57.8％。在一些家庭中发现了局灶性和全身性癫痫表型的重合。结论：纵向研究在癫痫流行病学中很重要。我们的结果反映了从基于人群的原始研究中仅选择功能良好的癫痫患者。

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