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首页> 外文期刊>European journal of gastroenterology and hepatology >Hepatitis E autochthonous infection in chronic liver disease.
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Hepatitis E autochthonous infection in chronic liver disease.

机译：慢性肝病中的戊型肝炎自发感染。

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摘要

Hepatitis E virus is endemic in many parts of the developing world and causes a self-limiting hepatitis in young adults, except in pregnant women and patients with chronic liver disease, where the mortality is high. Locally acquired hepatitis E is increasingly recognized in the developed world. It is caused by hepatitis E virus genotype 3, affects the middle-aged and the elderly, and may be a zoonotic infection from pigs. We present a case of locally acquired hepatitis E infection in a patient with previously undiagnosed cirrhosis, which resulted in subacute liver failure and death. We describe our attempt to trace this infection to a free-range pig farm adjacent to the patient's place of employment. Hepatitis E infection should be considered in the differential diagnosis in patients with decompensated chronic liver disease whatever their age or travel history. When found, the prognosis may be poor.
机译：戊型肝炎病毒在发展中国家的许多地方流行，并在年轻人中引起自限性肝炎，但孕妇和患有高死亡率的慢性肝病患者除外。本地获得的戊型肝炎在发达国家越来越得到认可。它是由戊型肝炎病毒基因型3引起的，影响中老年人，并且可能是猪的人畜共患病感染。我们介绍了一例先前未确诊的肝硬化患者的局部获得性戊型肝炎病毒感染，这导致亚急性肝衰竭和死亡。我们描述了将这种感染追溯到与患者工作地点相邻的一个散养猪场的尝试。对于失代偿性慢性肝病患者，无论其年龄或出行经历如何，在鉴别诊断时均应考虑戊型肝炎感染。如果发现，则预后可能较差。

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