首页> 外文期刊>European journal of gastroenterology and hepatology >Advanced hepatocellular carcinoma associated with cystic fibrosis.
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Advanced hepatocellular carcinoma associated with cystic fibrosis.

机译:晚期肝细胞癌合并囊性纤维化。

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Advances in the treatment of the respiratory complications of cystic fibrosis, including the availability of lung transplantation have led to a greater awareness of the manifestations of liver disease in up to 40% of patients with Cystic Fibrosis (CF). We report the case of an 18 year old female with CF who presented with advanced hepatocellular carcinoma and no prior clinical evidence of chronic liver disease. Hepatocellular carcinoma is usually the most severe manifestation of advanced cirrhosis although its development in non-cirrhotic cases of chronic liver disease has been reported. With the increasing life expectancy of CF patients it is likely that more unusual hepatic complications of this disease may be identified. Greater awareness may perhaps lead to earlier diagnosis in those at risk.
机译:囊性纤维化的呼吸系统并发症的治疗进展,包括可进行肺移植,已使多达40%的囊性纤维化(CF)患者对肝脏疾病的表现有了更高的认识。我们报道了一名18岁的女性CF患者,该女性患者患有晚期肝细胞癌,并且先前没有慢性肝病的临床证据。肝细胞癌通常是晚期肝硬化的最严重表现,尽管已有报道称其在慢性肝病的非肝硬化病例中会发展。随着CF患者的预期寿命的增加,可能会发现这种疾病的更多异常肝脏并发症。更高的认识可能会导致那些有风险的人尽早诊断。

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