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Non-surgical therapies of hepatocellular carcinoma.

机译:肝细胞癌的非手术疗法。

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摘要

Early detection of hepatocellular carcinoma (HCC) through surveillance programmes allows potentially curative therapies such as resection, liver transplantation and percutaneous ablation to be applied in 40% of the patients. In non-surgical candidates, percutaneous treatments are the best therapeutic approach, and may improve survival in patients with well preserved liver function and small tumours that achieve initial complete response. Applying these criteria 5-year survival rates above 50% are achieved. Radio frequency thermal ablation provides slightly better objective response rates than ethanol injection, but no survival advantages have been reported. At more advanced stages, only chemoembolization has been shown to improve survival in well-selected candidates.
机译:通过监视程序及早发现肝细胞癌(HCC),可以在40%的患者中采用诸如切除,肝移植和经皮消融之类的潜在治疗方法。在非手术候选人中,经皮治疗是最好的治疗方法,并且可以改善肝功能完好的肝小肿瘤患者的生存率,这些肿瘤可以达到最初的完全缓解。应用这些标准,可以达到50%以上的5年生存率。射频热消融提供比乙醇注射更好的客观反应率,但尚无生存优势的报道。在更高级的阶段,仅化学栓塞治疗已显示出可以改善精选患者的生存率。

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