首页> 外文期刊>European journal of gynaecological oncology >Conservative management of epithelial ovarian cancer.
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Conservative management of epithelial ovarian cancer.

机译:卵巢上皮癌的保守治疗。

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We are currently faced with a progressive delay in the age at which women conceive for the first time. This raises the possibility of the appearance of gynecologic disorders that may affect fertility, including neoplasms of the ovary. Fertility-sparing surgery is defined as the preservation of ovarian tissue in one or both adnexa and/or the uterus. Borderline ovarian tumor should be treated with conservative surgery. Salpingo-oophorectomy, or even ovarian cystectomy, are the procedures of choice, with recurrence rates of 2-3% and up to 20% if a simple cystectomy is performed. Cystectomy is indicated in patients with bilateral borderline tumors or in patients with a residual ovary. Borderline tumors with invasive peritoneal implants behave as an invasive cancer in 10-30% of cases with a survival rate of 10-66% compared with 100% in borderline tumors without invasive implants. Prophylactic oophorectomy is recommended when desire of conception has been accomplished. Conservative surgery in invasive epithelial ovarian cancer is limited to Stage IA, grade 1 tumor, and in some highly selected grade 2 tumors of serous, mucinous or endometrioid type, well-encapsulated and free of adhesions. The standard oncological surgical procedure with preservation of the uterus and normal appearing ovary is recommended. This includes salpingo-oophorectomy, excision of any suspicious peritoneal lesion, multiple peritoneal biopsies, appendectomy (particularly in mucinous tumors), and pelvic and paraaortic lymphadenectomy.
机译:我们目前正面临着女性首次怀孕年龄的逐渐推迟。这增加了可能影响生育力的妇科疾病出现的可能性,包括卵巢肿瘤。保留生育能力的手术定义为保留附件和/或子宫中的一个或两个卵巢组织。卵巢交界性肿瘤应采用保守手术治疗。输卵管卵巢切除术,甚至卵巢膀胱切除术是选择的方法,如果进行简单的膀胱切除术,其复发率为2-3%,最高可达20%。膀胱切除术适用于患有双侧交界性肿瘤的患者或卵巢残留的患者。带有浸润性腹膜植入物的交界性肿瘤在10-30%的病例中表现为浸润性癌,其生存率为10-66%,而没有浸润性腹膜植入物的交界性肿瘤的存活率为100%。当完成受孕的愿望时,建议进行预防性卵巢切除术。侵袭性上皮性卵巢癌的保守手术仅限于IA期,1级肿瘤,以及在一些高度选择的浆液性,粘液性或子宫内膜样类型的2级肿瘤中,其封装良好且无粘连。建议采用能保留子宫和正常卵巢的标准肿瘤外科手术程序。这包括输卵管卵巢切除术,任何可疑腹膜病变的切除,多次腹膜活检,阑尾切除术(特别是在粘液性肿瘤中)以及盆腔和主动脉旁淋巴结切除术。

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