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首页> 外文期刊>European journal of gynaecological oncology >Sequential recurrences of ovarian granulosa cell tumour 10 and 11 years after initial diagnosis as haemoperitoneum and subhepatic mass: a case report and review of the literature.
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Sequential recurrences of ovarian granulosa cell tumour 10 and 11 years after initial diagnosis as haemoperitoneum and subhepatic mass: a case report and review of the literature.

机译：卵巢颗粒细胞瘤的初步诊断为出血性腹膜和肝下肿块后的10和11年的顺序复发：病例报告和文献复习。

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摘要

Adult granulosa cell tumours (GCTs) are rare ovarian neoplasms characterised by an indolent course and a propensity for late recurrence. Due to frequent endocrine manifestations most GCTs are diagnosed at an early stage. However, clinical behaviour can not be safely predicted on the basis of conventional clinicopathologic parameters. Surgery remains the cornerstone of therapeutic management. We report on a rare case of a Stage IA GCT twice recurring ten and 11 years after initial surgical treatment. The first recurrence presented as an acute abdomen due to haemoperitoneum after tumour rupture. The second recurrence presented as a subhepatic mass. This case emphasises the need for extended, lifelong follow-up even for patients with early stage, apparently completely removed GCTs. Prognostic parameters and therapeutic options especially for patients with recurrent disease are discussed.
机译：成年的颗粒细胞瘤（GCT）是罕见的卵巢肿瘤，其特征是病程缓慢和晚期复发的倾向。由于频繁的内分泌表现，大多数GCT都是在早期诊断出来的。但是，不能根据常规临床病理参数安全地预测临床行为。手术仍然是治疗管理的基石。我们报告了一次罕见的I级GCT病例，该病例在初次手术治疗后的10年和11年两次复发。首次复发是由于肿瘤破裂后因血液腹膜而引起的急性腹部。第二次复发表现为肝下肿块。该病例强调甚至对于早期阶段，显然已完全切除的GCT患者，也需要进行长期的终身随访。讨论了特别是对于复发性疾病患者的预后参数和治疗选择。

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