Primary melanoma of the vagina is a rare and very aggressive tumor with an incidence of only 0.46 per one million women per year and less than 250 cases reported in the literature. Here the authors present a case of a 60-year-old woman, gravida 5, para 5, postmenopausal by 28 years, admitted to the Clinic for Obstetrics and Gynecology, with recurrent vaginal bleeding for the last year and with the complaint of a palpable tumor near the vaginal introitus. The preoperative biopsy revealed melanoma. CT scan did not prove she had distant metastasis. The patient was treated surgically, with wide local excision of four x five cm measured lesion and safety margins of two cm. Bilateral inguinal lymphadenectomy was performed. Follow-up five months after initial diagnosis, revealed no evidence of local recurrency or distant metastasis.
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机译：阴道原发性黑色素瘤是一种罕见且侵袭性极强的肿瘤，每年每百万名女性仅发生0.46例，文献报道少于250例。在这里，作者介绍了一例60岁女性，在妊娠28年前，绝经后28岁的孕妇gravida 5，para 5，该病入院是妇产科，去年阴道反复出血，且可触及明显肿瘤靠近阴道口。术前活检发现黑色素瘤。 CT扫描不能证明她有远处转移。对该患者进行了手术治疗，局部切除了4 x 5 cm的病变，安全距离为2 cm。进行了腹股沟双侧腹股沟淋巴结清扫术。初步诊断后五个月进行随访，未发现局部复发或远处转移的迹象。
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