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首页> 外文期刊>European journal of gynaecological oncology >Placental site trophoblastic tumor: report of a tertiary center experience
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Placental site trophoblastic tumor: report of a tertiary center experience

机译:胎盘部位滋养细胞肿瘤:三级中心经验报告

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Objective: To analyze the clinical and pathological characteristics of placental site trophoblastic tumor (PSTT) cases and to discuss the diagnosis, treatment, and prognosis of PSTT. Materials and Methods: The clinical and pathological data of eight patients with PSTT at Istanbul Medical Faculty Hospital from 1988 to 2010 were analyzed retrospectively. Results: The mean age of the patients was 31 years. The antecedent pregnancy was full-term delivery in most of the patients (6/8, 75%). The mean interval from last pregnancy to diagnosis of Pm was 35 months (range, six to 192). Serum human chorionic gonadotropin (hCG) levels at the time of diagnosis ranged from 0.1 to 2280 mIU/ml (mean, 614). All patients had Stage 1 disease and ultimately underwent hysterectomy. None of the patients received adjuvant chemotherapy. One patient died of an unknown reason, one month after the surgery. The rest of the patients were alive and without evidence of disease after an average of 3.5 years (range, one to 11) of follow-up. Conclusion: Hysterectomy alone can provide long-term survival in early-stage disease.
机译:目的:分析胎盘部位滋养细胞肿瘤(PSTT)的临床和病理特点,探讨PSTT的诊断,治疗和预后。资料与方法:回顾性分析1988年至2010年在伊斯坦布尔医科大学医院收治的8例PSTT患者的临床和病理资料。结果:患者的平均年龄为31岁。在大多数患者中,足月妊娠是足月分娩(6 / 8,75%)。从上次妊娠到诊断为Pm的平均间隔为35个月(范围从6到192)。诊断时的血清人绒毛膜促性腺激素(hCG)水平范围为0.1至2280 mIU / ml(平均614)。所有患者均患有1期疾病,并最终接受了子宫切除术。没有患者接受辅助化疗。手术后一个月,一名患者因未知原因死亡。在平均随访3.5年(范围从1到11年)后,其余患者仍然活着并且没有疾病迹象。结论:仅子宫切除术可在早期疾病中提供长期生存。

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