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首页> 外文期刊>European journal of gynaecological oncology >Comparison of whole-body PET/PET-CT and conventional imaging procedures for distant metastasis staging in patients with breast cancer: a meta-analysis
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Comparison of whole-body PET/PET-CT and conventional imaging procedures for distant metastasis staging in patients with breast cancer: a meta-analysis

机译：全身PET / PET-CT与常规影像学方法对乳腺癌远处转移分期的比较：一项荟萃分析

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Aim: To compare the performance of whole-body PET/PET-CT with that of conventional imaging procedures for the overall assessment of distant metastasis in patients with breast cancer. Materials and Methods: The authors performed a meta-analysis of all available studies of whole-body PET/PET-CT compared with conventional imaging procedures. They calculated sensitivities, specificities, positive likelihood ratios, negative likelihood ratios, and constructed summary receiver operating characteristic (ROC) curves using bivariate regression models for whole-body PET/PET-CT and conventional imaging procedures, respectively. Results: Across six studies (609 patients), sensitivity, specificity, positive likelihood ratios, and negative likelihood ratios of whole-body PET/PET-CT were 0.99 (95% confidence interval [CI] = 0.88-1.00), 0.95 (95% CI = 0.89-0.98), 21.1 (95% CI = 8.2-55.5), and 0.02 (95% CI = 0.001-0.13), respectively, and of conventional imaging procedures they were 0.57 (95% CI = 0.37-0.74), 0.88 (95% CI = 0.78-0.94), 4.8 (95% CI = 2.8-8.2) and 0.49 (95% CI = 0.33-0.74), respectively. Conclusion: Compared with conventional imaging procedures, whole-body PET/PET-CT had excellent diagnostic performance for distant metastasis staging in patients with breast cancer.
机译：目的：比较全身PET / PET-CT与常规影像学检查对乳腺癌患者远处转移的总体表现。材料和方法：作者对与常规成像方法相比对全身PET / PET-CT的所有可用研究进行了荟萃分析。他们分别使用全身PET / PET-CT和常规成像程序的双变量回归模型计算了敏感性，特异性，正似然比，负似然比，并构建了摘要接收者操作特征（ROC）曲线。结果：在六项研究（609例患者）中，全身PET / PET-CT的敏感性，特异性，阳性似然比和阴性似然比分别为0.99（95％置信区间[CI] = 0.88-1.00），0.95（95） ％CI = 0.89-0.98），21.1（95％CI = 8.2-55.5）和0.02（95％CI = 0.001-0.13），在常规成像程序中它们分别为0.57（95％CI = 0.37-0.74）分别为0.88（95％CI = 0.78-0.94），4.8（95％CI = 2.8-8.2）和0.49（95％CI = 0.33-0.74）。结论：与常规影像学检查相比，全身PET / PET-CT对乳腺癌患者远处转移分期具有出色的诊断性能。

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