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首页> 外文期刊>European heart journal cardiovascular Imaging >Magnetic resonance myocardial perfusion imaging at 3.0 Tesla for the identification of myocardial ischaemia: comparison with coronary catheter angiography and fractional flow reserve measurements
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Magnetic resonance myocardial perfusion imaging at 3.0 Tesla for the identification of myocardial ischaemia: comparison with coronary catheter angiography and fractional flow reserve measurements

机译：3.0特斯拉磁共振心肌灌注显像用于鉴定心肌缺血：与冠状动脉导管造影和分数血流储备测量值的比较

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摘要

To assess image quality and diagnostic performance of 3.0 Tesla (3T) cardiac magnetic resonance (CMR) myocardial perfusion imaging with a dual radiofrequency source to detect functional relevant coronary artery disease (CAD), using coronary angiography and invasive pressure-derived fractional flow reserve (FFR) as reference standard.We included 116 patients with suspected or known CAD, who underwent 3T adenosine myocardial perfusion CMR (resolution 2.97 x 2.97 mm) and coronary angiography plus FFR measurements in intermediate lesions. Image quality of myocardial perfusion CMR was graded on a 4-point scale (1 = poor to 4 = excellent). Diagnostic accuracy was assessed by ROC analyses using a 16-myocardial segment-based summed perfusion score (0 = normal to 3 = transmural perfusion defect) and by determining sensitivity, specificity, positive and negative predictive value on the coronary vessel territory and the patient level. Diagnostic image quality was achieved for all stress myocardial perfusion CMR studies with an average quality score of 2.5,3.1, and 3.0 for LAD, LCX, and RCA. territories. The ability of the myocardial perfusion CMR perfusion score to detect significant coronary artery stenosis yielded an area under the curve of 0.93 on ROC analysis. Values for sensitivity, specificity, positive and negative predictive value on a vessel territory level and the patient level were 89,95, 87, 96% and 85, 87,77,92%, respectively.In patients with suspected or known significant CAD, 3T myocardial perfusion CMR with standard perfusion protocols provides consistently high image quality and an excellent diagnostic performance.
机译：为了评估3.0特斯拉（3T）心脏磁共振（CMR）心肌灌注成像的图像质量和诊断性能，该技术使用双射频源使用冠状动脉造影和有创压力衍生的分流储备来检测功能性相关冠状动脉疾病（CAD）（ FFR）作为参考标准。我们纳入了116例疑似或已知的CAD患者，他们接受了3T腺苷心肌灌注CMR（分辨率2.97 x 2.97 mm）和冠状动脉造影以及FFR测量中间病变。心肌灌注CMR的图像质量按4分制评分（1 =差至4 =优）。通过使用基于16个心肌节段的总灌注评分（0 =正常至3 =透壁灌注缺陷）的ROC分析以及确定冠状血管区域和患者水平的敏感性，特异性，阳性和阴性预测值，通过ROC分析评估诊断准确性。所有压力心肌灌注CMR研究均获得诊断图像质量，LAD，LCX和RCA的平均质量得分分别为2.5、3.1和3.0。领土。在ROC分析中，心肌灌注CMR灌注评分检测到明显冠状动脉狭窄的能力在0.93曲线下产生了一个区域。在可疑或已知显着CAD的患者中，血管区域和患者水平的敏感性，特异性，阳性和阴性预测值分别为89,95、87、96％和85、87,77,92％。具有标准灌注方案的3T心肌灌注CMR可提供一致的高图像质量和出色的诊断性能。

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