Re: Phase III study of molecularly targeted adjuvant therapy in locally advanced urothelial cancer of the bladder based on p53 status

FlaigT.W.; TheodorescuD.

首页> 外文期刊>European urology >Re: Phase III study of molecularly targeted adjuvant therapy in locally advanced urothelial cancer of the bladder based on p53 status

【24h】

Re: Phase III study of molecularly targeted adjuvant therapy in locally advanced urothelial cancer of the bladder based on p53 status

机译：回复：基于p53状态的分子靶向辅助治疗在局部晚期膀胱尿路上皮癌中的III期研究

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Experts' summary:Retrospective evaluations had suggested that p53 dysregula-tion is prognostic and predictive of response to cytotoxic chemotherapy in bladder cancer. This phase 3 study assessed tumors from postcystectomy patients with pT1-2 NO MO bladder cancer for p53 overexpression. Mutant p53 is stabilized and detectable by immunohistochemistry, whereas wild-type p53 is quickly degraded.

机译：专家总结：回顾性评估表明，p53失调可预后并预测膀胱癌对细胞毒性化学疗法的反应。这项3期研究评估了来自pT1-2 NO MO膀胱癌的膀胱切除术后患者的肿瘤中p53的过度表达。 p53突变体可以通过免疫组织化学稳定和检测，而野生型p53则可以快速降解。

著录项

来源
《European urology》 |2012年第1期|共2页
作者
FlaigT.W.; TheodorescuD.;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类泌尿科学（泌尿生殖系疾病）;
关键词

相似文献

外文文献
中文文献
专利

1. Re: Phase III study of molecularly targeted adjuvant therapy in locally advanced urothelial cancer of the bladder based on p53 status [J] . FlaigT.W., TheodorescuD. European urology . 2012,第1期

机译：回复：基于p53状态的分子靶向辅助治疗在局部晚期膀胱尿路上皮癌中的III期研究
2. Re: Phase III study of molecularly targeted adjuvant therapy in locally advanced urothelial cancer of the bladder based on p53 status [J] . WoodD.P. The Journal of Urology . 2012,第6期

机译：回复：基于p53状态的分子靶向辅助治疗在局部晚期膀胱尿路上皮癌中的III期研究
3. Phase III study of molecularly targeted adjuvant therapy in locally advanced urothelial cancer of the bladder based on p53 status. [J] . Stadler WM, Lerner SP, Groshen S, Journal of Clinical Oncology . 2011,第25期

机译：基于p53状态的局部靶向膀胱尿路上皮癌分子靶向辅助治疗的III期研究。
4. Adjuvant Neutron Therapy in Complex Treatment of Patients with Locally Advanced Breast Cancer [C] . V. A. Lisin, V. V. Velikaya, Zh. A. Startseva, International Conference on Physics of Cancer : Interdisciplinary Problems and Clinical Applications . 2017

机译：佐剂中子治疗复杂治疗局部晚期乳腺癌患者
5. Treatment patterns, costs and outcomes of systemic chemotherapy, adjuvant intravesical therapy, and surveillance for urothelial bladder cancer. [D] . Kerrigan, Matthew Charles. 2007

机译：全身化疗，辅助膀胱内治疗和尿路上皮膀胱癌监测的治疗方式，费用和结果。
6. Phase III Study of Molecularly Targeted Adjuvant Therapy in Locally Advanced Urothelial Cancer of the Bladder Based on p53 Status [O] . Walter M. Stadler, Seth P. Lerner, Susan Groshen, -1

机译：基于p53状态的局部晚期膀胱癌分子靶向辅助治疗的III期研究
7. Re: Phase III Study of Molecularly Targeted Adjuvant Therapy in Locally Advanced Urothelial Cancer of the Bladder Based on p53 Status [O] . Thomas W. Flaig, Dan Theodorescu 2012

机译：RE：基于P53状态的膀胱局部晚期尿路上皮癌分子靶向辅助治疗的第III期研究

Re: Phase III study of molecularly targeted adjuvant therapy in locally advanced urothelial cancer of the bladder based on p53 status

摘要

著录项

相似文献

相关主题

期刊订阅