Expression and clinical implication of Beclin1, HMGB1, p62, survivin, BRCA1 and ERCC1 in epithelial ovarian tumor tissues

Ju L. -L.; Zhao C. Y.; Ye K. -F.; Yang H.; Zhang J.

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Expression and clinical implication of Beclin1, HMGB1, p62, survivin, BRCA1 and ERCC1 in epithelial ovarian tumor tissues

机译：Beclin1，HMGB1，p62，survivin，BRCA1和ERCC1在卵巢上皮性肿瘤组织中的表达及其临床意义

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OBJECTIVE: The aim of the present study is to investigate the differential expression of Beclin1, HMGB1, p62, survivin, ER-CC1 and BRCA1 protein in epithelial ovarian cancer (EOC) and to evaluate the relationship between autophagy and platinum resistance of EOC patients during platinum-based chemotherapy with the protein expression.

机译：目的：研究Beclin1，HMGB1，p62，survivin，ER-CC1和BRCA1蛋白在上皮性卵巢癌（EOC）中的差异表达，并评估EOC患者自噬与铂耐药之间的关系。铂类化学疗法具有蛋白质表达功能。

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《European review for medical and pharmacological sciences.》 |2016年第10期|共11页
作者
Ju L. -L.; Zhao C. Y.; Ye K. -F.; Yang H.; Zhang J.;
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正文语种 eng
中图分类药理学;
关键词
Epithelial ovarian tumor tissues; Autophagy; Beclin1; HMGB1; p62; Survivin; ERCC1; BRCA1; Platinum-sensitive; Platinum-resistant;

机译：上皮性卵巢肿瘤组织;自噬;Beclin1;HMGB1;p62;Survivin;ERCC1;BRCA1;对铂敏感;对铂耐药;

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1. Expression and clinical implication of Beclin1, HMGB1, p62, survivin, BRCA1 and ERCC1 in epithelial ovarian tumor tissues [J] . Ju L. -L., Zhao C. Y., Ye K. -F., European review for medical and pharmacological sciences. . 2016,第10期

机译：Beclin1，HMGB1，p62，survivin，BRCA1和ERCC1在卵巢上皮性肿瘤组织中的表达及其临床意义
2. Association of expression of p53, livin, ERCC1, BRCA1 and PARP1 in epithelial ovarian cancer tissue with drug resistance and prognosis [J] . Pathology Research and Practice . 2020,第2期

机译：P53，Livin，Ercc1，BRCA1和PARP1在上皮性卵巢癌组织中表达的关系耐药性和预后
3. Pre-treatment tumor expression of ERCC1 in women with advanced stage epithelial ovarian cancer is not predictive of clinical outcomes: A gynecologic oncology group study [J] . RubattJ.M., DarcyK.M., TianC., Gynecologic Oncology: An International Journal . 2012,第2期

机译：妇科肿瘤学小组研究表明，ERCC1在晚期卵巢上皮癌妇女中的治疗前肿瘤表达不能预测临床结果
4. The Comparison of Glycosphingolipids in an Epithelial Ovarian Cancer Cell Line and a Nontumorigenic Epithelial Ovarian Cell Line using MALDI-MS [C] . Krishani K. Rajanayake, William R. Taylor, Dragan Isailovic ASMS Conference on Mass Spectrometry and Allied Topics . 2016

机译：使用MALDI-MS对上皮性卵巢癌细胞系中糖磷脂和非致素上皮性卵巢细胞系的比较
5. Gene expression analysis of human non -small cell lung cancer subtypes, adenocarcinoma and squamous cell carcinoma, and mouse lung epithelial cell lines: Implications in lung tumorigenesis [D] . Silvers, Amy Lynn. 2002

机译：人类非小细胞肺癌亚型，腺癌和鳞状细胞癌以及小鼠肺上皮细胞系的基因表达分析：在肺肿瘤发生中的意义
6. Pre-Treatment Tumor Expression of ERCC1 in Women with Advanced Stage Epithelial Ovarian Cancer is Not Predictive of Clinical Outcomes [O] . Jennifer M. Rubatt, Kathleen M. Darcy, Chunqiao Tian, -1

机译：患有先进阶段上皮卵巢癌的妇女中ERCC1的前治疗肿瘤表达并未预测临床结果
7. Pre-treatment tumor expression of ERCC1 in women with advanced stage epithelial ovarian cancer is not predictive of clinical outcomes: A gynecologic oncology group study [O] . Jennifer M. Rubatt, Kathleen M. Darcy, Chunqiao Tian, 2012

机译：患有晚期上皮性卵巢癌患者的妇女的前治疗肿瘤表达并未预测临床结果：妇科肿瘤学群体研究
8. Modeling Human Epithelial Ovarian Cancer in Mice by Alteration of Expression of the Expression of the BRCA1 and/p53 Genes [R] . Connolly, D. C. 2006

机译：通过改变BRCa1和/ p53基因表达对小鼠人卵巢上皮性癌的建模

Expression and clinical implication of Beclin1, HMGB1, p62, survivin, BRCA1 and ERCC1 in epithelial ovarian tumor tissues

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