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Metabolomics of urinary tract infection: A new uroscope in town

机译:尿路感染的代谢组学:镇上的新型输尿管镜

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摘要

Urinary tract infection (UTI) is a potentially life-threatening infectious disease. For rapid directed therapy of UTIs, it is essential to determine the causative microorganism. To date, there is no single test that has been proven to reliably, rapidly and accurately identify the etiologic organism in UTI. The molecular methods for diagnosing the cause of UTI and prognostic development of clinically important metabolomic evaluations and their limitations for use in the diagnosis and monitoring of infections are discussed in this review article. The application of the emerging investigative device NMR spectroscopy as a surrogate method for the diagnosis of UTI is also addressed.
机译:尿路感染(UTI)是一种潜在的威胁生命的传染病。对于UTI的快速定向治疗,确定病原微生物至关重要。迄今为止,还没有单一测试能够可靠,快速和准确地识别UTI中的病原生物。这篇综述文章讨论了诊断UTI病因和临床上重要的代谢组学评估的预后发展的分子方法及其在感染的诊断和监测中的局限性。还探讨了新兴的研究性设备NMR光谱作为替代方法诊断UTI的应用。

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