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首页> 外文期刊>European radiology >Chronic obstructive pulmonary disease (COPD) patients with osteoporotic vertebral compression fractures (OVCFs): Improvement of pulmonary function after percutaneous vertebroplasty (VTP)
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Chronic obstructive pulmonary disease (COPD) patients with osteoporotic vertebral compression fractures (OVCFs): Improvement of pulmonary function after percutaneous vertebroplasty (VTP)

机译：患有骨质疏松性椎体压缩性骨折（OVCF）的慢性阻塞性肺疾病（COPD）：经皮椎体成形术（VTP）后肺功能的改善

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Objectives: To investigate the changes of respiratory function in patients affected by chronic obstructive pulmonary disease (COPD) with single dorsal osteoporotic vertebral compression fractures (OVCFs) treated with vertebroplasty (VTP). Methods: Forty-five patients affected by COPD and single dorsal OVCF underwent VTP (29 men, 16 women; mean age 71.4 years, range 65-77 years). Inclusion criteria were magnetic resonance findings of bone marrow oedema, without intracanal bone fragments and refractory pain to medical treatment for at least 3 months. Osteoporosis was assessed by bone densitometry. Spirometry was performed before and after treatment. Results: A significant VAS-score decrease was observed 1 week after VTP, with a subsequent decrease over time; vital capacity (VC) and forced vital capacity (FVC) improved over time, reaching a plateau at 3 months. Forced expiratory volume at 1 s (FEV1) did not significantly differ between the pre-VTP values and follow-up values. A significant correlation was observed between VAS-score values and VC, and VAS-score values and FVC. No significant correlation was observed between VAS-score values and FEV1 values. Conclusions: VTP improves restrictive ventilatory impairment in patients with moderate and severe COPD affected by single thoracic OVCFs. We recommend this treatment in the management of these patients. Key Points: ? Osteoporosis is a major comorbidity in chronic obstructive pulmonary disease (COPD) patients. ? Pain due to osteoporotic vertebral compression fractures worsens respiratory failure in COPD. ? Vertebroplasty improves ventilatory impairment in COPD patients with osteoporotic vertebral compression fractures.
机译：目的：探讨经椎体成形术（VTP）治疗的慢性阻塞性肺疾病（COPD）伴有单个背侧骨质疏松性椎体压缩性骨折（OVCF）的患者的呼吸功能变化。方法：45名受COPD和单背OVCF影响的患者接受了VTP（男29例，女16例;平均年龄71.4岁，范围65-77岁）。纳入标准为磁共振检查发现的骨髓水肿，未见管内骨碎片和难治性疼痛，至少治疗3个月。通过骨密度测定法评估骨质疏松症。在治疗前后进行肺活量测定。结果：VTP后1周观察到VAS评分显着下降，随后随时间下降;肺活量（VC）和强制肺活量（FVC）随着时间的推移而有所改善，在3个月时达到稳定水平。 VTP前值和随访值之间在1 s时的呼气量（FEV1）没有显着差异。在VAS分数值和VC以及VAS分数值和FVC之间观察到显着相关性。在VAS得分值和FEV1值之间未观察到显着相关性。结论：VTP改善了单胸OVCF影响的中重度COPD患者的限制性通气障碍。我们建议在这些患者的治疗中采用这种治疗方法。关键点： ？骨质疏松症是慢性阻塞性肺疾病（COPD）患者的主要合并症。 ？骨质疏松性椎体压缩性骨折引起的疼痛加剧了COPD的呼吸衰竭。 ？椎体成形术可改善患有骨质疏松性椎体压缩性骨折的COPD患者的通气障碍。

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