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首页> 外文期刊>European radiology >Borderline breast lesions: comparison of malignancy underestimation rates with 14-gauge core needle biopsy versus 11-gauge vacuum-assisted device.
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Borderline breast lesions: comparison of malignancy underestimation rates with 14-gauge core needle biopsy versus 11-gauge vacuum-assisted device.

机译：边缘性乳腺病变：14针芯活检与11针真空辅助装置的恶性肿瘤低估率比较。

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OBJECTIVE: To compare malignancy underestimation rates in the case of percutaneous diagnosis of borderline breast lesions(B3) at 14-g core-needle-biopsy (CNB) and at 11-g vacuum-assisted-biopsy (VAB). METHODS: The histological results of 4764 image-guided breast biopsies were retrospectively reviewed. 300 B3, 151 benign papillomas, 88 radial sclerosing lesions, 46 lobular neoplasia, 15 atypical ductal hyperplasia diagnosed at ultrasound-guided 14-g CNB (76%) or stereotactically-guided 11-g VAB (24%) were identified. On average, 5 cores were obtained with CNB and 12 with VAB. Biopsy variables were reviewed and correlated with surgical excision or follow-up (>24 months). Lesion- and device-specific underestimation rates of malignancy were calculated. RESULTS: Surgical excision was performed on 237 lesions: 178 were benign, 21 atypical, 38 cancers. The remaining 63 lesions were unchanged at follow-up. Overall malignancy underestimation rate was 12.7% at 14-g CNB and 12.5% at 11-g VAB. Based on excision histology or follow-up, lesion-specific underestimation rates were: benign papillomas: 14-g CNB 11%, 11-g VAB 0%; RSL: 14-g CNB 6%, 11-g VAB 4%; LN: 14-g CNB 40%, 11-g VAB 23%; ADH: 14-g CNB 33%; 11-g VAB 22%. CONCLUSION: In the case of percutaneous diagnosis of B3 lesions, underestimation of malignancy occurs regardless of the biopsy method.
机译：目的：比较经皮诊断为边缘性乳腺病变（B3）的14 g芯针活检（CNB）和11 g真空辅助活检（VAB）的恶性肿瘤低估率。方法：回顾性分析了4764例图像引导的乳腺活检的组织学结果。确定了300 B3、151例良性乳头状瘤，88例放射状硬化性病变，46例小叶肿瘤，15例超声引导的14 g CNB（76％）或立体定向引导的11 g VAB（24％）诊断的非典型导管增生。平均而言，使用CNB获得5个核心，使用VAB获得12个核心。回顾了活检变量，并将其与手术切除或随访（> 24个月）相关联。计算了特定于病变部位和特定部位的恶性肿瘤低估率。结果：手术切除了237个病变：178例良性，21例非典型性，38例癌症。其余63个病灶在随访中未改变。在14克CNB时，总的恶性肿瘤低估率是12.7％，在11克VAB时是12.5％。根据切除组织学或随访结果，病变特异性低估率是：良性乳头状瘤：14克CNB为11％，11克VAB为0％; RSL：14克CNB 6％，11克VAB 4％; LN：14克CNB 40％，11克VAB 23％; ADH：14-g CNB 33％; 11克VAB 22％。结论：在经皮诊断B3病变的情况下，无论活检方法如何，都会低估恶性肿瘤的发生。

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