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首页> 外文期刊>Experimental and therapeutic medicine >Marchiafava-Bignami disease with rare etiology: A case report
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Marchiafava-Bignami disease with rare etiology: A case report

机译：病因少见的Marchiafava-Bignami病：一例报告

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摘要

A male, 62-year-old patient was admitted to hospital due to dizziness and gait disturbance for 10 days. The patient had fallen a few times due to the gait instability, which was associated with stiffness and memory loss. The patient had undergone cardiac carcinoma surgery three years previously and had no drinking history. Physical examination revealed that the patient was lucid when conscious but exhibited slurred speech, apathy and cognitive impairment. The finger-to-nose and rapid alternating movement tests showed the patient to be slightly clumsy. Magnetic resonance imaging revealed symmetric abnormal signals in the splenium of the corpus callosum, and the diagnosis was Marchiafava-Bignami disease (MBD). The patient recovered following the administration of vitamin B and other treatments. The patient had long-term appetite loss. A brain myelin metabolism disorder caused by long-term malnutrition and leading to demyelinating changes in the brain may have been the cause of the MBD of this patient. Clinicians should increase awareness of this disease and should not ignore the diagnosis of it, even when the patient lacks a drinking history. Early diagnosis and treatment can improve the prognosis of the patient.
机译：一名62岁的男性患者因头晕和步态障碍入院10天。由于步态不稳，患者跌倒了几次，步态不稳与僵硬和记忆力下降有关。该患者三年前接受过心脏癌手术，没有饮酒史。体格检查表明患者清醒时清醒，但表现出言语不清，冷漠和认知障碍。手指到鼻子的快速交替运动测试表明患者有点笨拙。磁共振成像显示call体脾中存在对称异常信号，诊断为马尔基法瓦-比尼亚米病（MBD）。服用维生素B和其他治疗后，患者康复了。该患者长期食欲不振。由长期营养不良导致的大脑髓磷脂代谢紊乱并导致大脑中的脱髓鞘变化可能是该患者MBD的原因。即使患者缺乏饮酒史，临床医生也应提高对这种疾病的认识，并且不应忽视对它的诊断。早期诊断和治疗可以改善患者的预后。

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