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首页> 外文期刊>Expert opinion on pharmacotherapy >Evaluation of injection force of three insulin delivery pens.
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Evaluation of injection force of three insulin delivery pens.

机译：评价三支胰岛素输送笔的注射力。

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OBJECTIVE: Reduced injection force is among the modifications to the Next Generation FlexPen (NGFP). This force was compared with two other prefilled pens: SoloStar (SS) and KwikPen (KP). Research design/methods: The injection force of the pens was measured, with either a BD Micro-Fine 31G thin-wall needle, or a NovoFine 32G Tip extra thin wall needle attached. Pens of each type were tested with both needles, during injection of 20 U insulin, at speeds 3.3, 5 and 8.3 mm/s. RESULTS: NGFP had a significantly (p < 0.05) lower mean injection force than SS or KP, at all injection speeds, with both needles. Injection forces (mean +/- s.d.) with NGFP and the BD Micro-Fine() 31G thin-wall needle were: 8.1 +/- 0.7, 10.7 +/- 1.4 and 15.6 +/- 0.9 N at the three speeds, respectively. For SS, the corresponding values were: 9.2 +/- 0.5, 13.3 +/- 0.8 and 20.7 +/- 2.4 N. For KP they were: 12.5 +/- 1.6, 16.9 +/- 1.2 and 24.5 +/- 2.6 N. Attached to the NovoFine 32G Tip extra thin wall needle, the NGFP injection forces were: 5.7 +/- 0.4, 8.2 +/- 0.7 and 12.7 +/- 0.5 N; with SS were: 6.7 +/- 0.3, 10.4 +/- 2.1 and 16.3 +/- 1.1 N; and with KP were: 9.1 +/- 1.3, 13.1 +/- 0.8 and 21.6 +/- 2.0 N. The injection force with NGFP was 12 - 25% lower compared with SS and 35 - 41% lower compared with KP. CONCLUSIONS: This study shows that NGFP has a significantly lower injection force than SS or KP.
机译：目的：降低注射力是对下一代FlexPen（NGFP）的修改之一。将该力与另外两支预填充笔进行了比较：SoloStar（SS）和KwikPen（KP）。研究设计/方法：用BD Micro-Fine 31G薄壁针头或NovoFine 32G Tip超薄壁针头测量笔的注射力。在注射20 U胰岛素的过程中，以3.3、5和8.3 mm / s的速度用两根针测试每种类型的笔。结果：在所有注射速度下，两个针头的NGFP均值注射力均显着低于（p <0.05）SS或KP。 NGFP和BD Micro-Fine（）31G薄壁针的注射力（平均+/- sd）在三种速度下分别为：8.1 +/- 0.7、10.7 +/- 1.4和15.6 +/- 0.9 N 。对于SS，相应的值是：9.2 +/- 0.5、13.3 +/- 0.8和20.7 +/- 2.4 N.对于KP，它们是：12.5 +/- 1.6、16.9 +/- 1.2和24.5 +/- 2.6 N连接到NovoFine 32G Tip超薄壁针上时，NGFP的注射力为：5.7 +/- 0.4 N，8.2 +/- 0.7 N和12.7 +/- 0.5N。 SS为：6.7 +/- 0.3、10.4 +/- 2.1和16.3 +/- 1.1N;和KP分别为：9.1 +/- 1.3、13.1 +/- 0.8和21.6 +/- 2.0N。NGFP的注射力比SS低12-25％，与KP相比低35-41％。结论：这项研究表明，NGFP的注射力明显低于SS或KP。

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