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首页> 外文期刊>Expert opinion on pharmacotherapy >Treatment strategies for nonmotor manifestations of Parkinson's disease.
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Treatment strategies for nonmotor manifestations of Parkinson's disease.

机译：帕金森氏病非运动表现的治疗策略。

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To date, Parkinson's disease tends to have been perceived mainly as a disorder affecting the extrapyramidal motor system and leading to tremor, bradykinesia, rigidity, and--in later stages--postural instability. However, it is now apparent that patients frequently experience additional clinical symptoms, such as pain, autonomic and sensory dysfunction, neuropsychiatric disorders and sleep disorders. These symptoms often impair patients' quality of life to a greater extent than the motor symptoms. Treatment of these nonmotor features is mandatory and directly improves quality of life. Unfortunately, hardly any double-blind, randomized, controlled studies are available, with the consequence that most recommendations are not based on the highest level of evidence.
机译：迄今为止，帕金森氏病往往主要被认为是一种影响锥体束外运动系统并导致震颤，运动迟缓，僵硬以及在后期阶段姿势不稳的疾病。但是，现在很明显，患者经常经历其他临床症状，例如疼痛，自主神经和感觉功能障碍，神经精神疾病和睡眠障碍。这些症状通常比运动症状更严重地损害患者的生活质量。这些非运动功能的治疗是强制性的，可直接改善生活质量。不幸的是，几乎没有任何双盲，随机，对照研究可用，因此大多数建议并非基于最高证据水平。

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