Delamanid when other anti-tuberculosis-treatment regimens failed due to resistance or tolerability

Kwon Yong-Soo; Jeong Byeong-Ho; Koh Won-Jung

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Delamanid when other anti-tuberculosis-treatment regimens failed due to resistance or tolerability

机译：当其他抗结核治疗方案由于耐药性或耐受性而失败时的德拉曼尼德

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Introduction: The limited availability of effective drugs causes difficulties in the management of multidrug-resistant tuberculosis (MDR-TB) and novel therapeutic agents are needed. Delamanid, a new nitro-hydro-imidazooxazole derivative, inhibits mycolic acid synthesis. This review covers the efficacy and safety of delamanid for MDR-TB.

机译：简介：有效药物的有限供应给耐多药结核病（MDR-TB）的管理造成了困难，因此需要新型治疗剂。新的硝基氢-咪唑并恶唑衍生物德拉曼尼德抑制霉菌酸的合成。这篇综述涵盖了德拉曼尼德治疗耐多药结核病的有效性和安全性。

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《Expert opinion on pharmacotherapy》 |2015年第2期|共9页
作者
Kwon Yong-Soo; Jeong Byeong-Ho; Koh Won-Jung;
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原文格式 PDF
正文语种 eng
中图分类药学;
关键词
antitubercular agents; delamanid; multidrug-resistant tuberculosis; tuberculosis;

机译：抗结核药;地拉曼胺;耐多药结核;结核;

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专利

1. Delamanid when other anti-tuberculosis-treatment regimens failed due to resistance or tolerability [J] . Kwon Yong-Soo, Jeong Byeong-Ho, Koh Won-Jung Expert opinion on pharmacotherapy . 2015,第Pta2期

机译：当其他抗结核治疗方案由于耐药性或耐受性而失败时的德拉曼尼德
2. Efficacy, safety, and tolerability of a 24-month treatment regimen including delamanid in a child with extensively drug-resistant tuberculosis A case report and review of the literature [J] . Esposito Susanna, Bosis Samantha, Tadolini Marina, Medicine. . 2016,第46期

机译：24个月治疗方案的疗效，安全性和耐受性，包括具有广泛耐药结核的儿童中的Delamanid一种案例报告和文献审查
3. Efficacy and tolerability of a double boosted protease inhibitor (lopinavir + saquinavir/ritonavir) regimen in HIV-infected patients who failed treatment with nonnucleoside reverse transcriptase inhibitors. [J] . Chetchotisakd P, Anunnatsiri S, Mootsikapun P, HIV medicine . 2007,第8期

机译：双重增强蛋白酶抑制剂（洛匹那韦+沙奎那韦/利托那韦）方案在HIV感染的非核苷类逆转录酶抑制剂治疗失败的患者中的疗效和耐受性。
4. Impact of Drug Selection and Dosing Regimens on GI Tract Concentrations and Antimicrobial Resistance [C] . Conference of the American College of Veterinary Internal Medicine (ACVIM) . 2017

机译：药物选择和给药方案对胃肠道浓度和抗微生物抗性的影响
5. An examination of the Index of Readiness as a predictor of adherence and an adherence intervention in HIV+ males who repeatedly failed anti-HIV treatment regimens (Immune deficiency). [D] . Enriquez, Maithe. 2002

机译：检查准备指数是否可作为依从性的预测指标以及对反复失败的抗HIV治疗方案（免疫缺陷）的HIV +男性的依从性干预。
6. Efficacy safety and tolerability of a 24-month treatment regimen including delamanid in a child with extensively drug-resistant tuberculosis [O] . Susanna Esposito, Samantha Bosis, Marina Tadolini, -1

机译：包括广泛耐药结核病儿童在内的包括德拉曼胺在内的24个月治疗方案的疗效安全性和耐受性
7. Efficacy, safety, and tolerability of a 24-month treatment regimen including delamanid in a child with extensively drug-resistant tuberculosis [O] . Susanna Esposito, Samantha Bosis, Marina Tadolini, 2016

机译：24个月治疗方案的疗效，安全性和耐受性，包括具有广泛耐药结核病的儿童中的Delamanid

Delamanid when other anti-tuberculosis-treatment regimens failed due to resistance or tolerability

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