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Targeting adiponectin for cardioprotection.

机译:靶向脂联素进行心脏保护。

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摘要

Adiponectin is an adipose tissue-derived plasma protein which has a reduced concentration in subjects with obesity-related diseases. Adiponectin has antidiabetic and anti-inflammatory characteristics, which lead to beneficial actions on various obesity-linked complications. Recent experimental findings have shown that adiponectin contributes to protection against cardiac remodelling after pressure overload and cardiac injury following ischaemia-reperfusion. Thus, adiponectin could emerge as a potential cardioprotective agent for the treatment of several pathological heart conditions.
机译:脂联素是源自脂肪组织的血浆蛋白,其在患有肥胖症相关疾病的受试者中具有降低的浓度。脂联素具有抗糖尿病和抗炎的特性,从而导致对各种肥胖相关并发症的有益作用。最近的实验发现表明,脂联素有助于防止压力超负荷后的心脏重塑和缺血再灌注后的心脏损伤。因此,脂联素可能会成为潜在的心脏保护剂,可用于治疗多种病理性心脏病。

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