...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Experimental Gerontology >Age-dependent effects of treadmill exercise during a period of inactivity.
【24h】

Age-dependent effects of treadmill exercise during a period of inactivity.

机译：不运动期间跑步机锻炼的年龄依赖性效应。

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The objective of this study was to investigate the effect of a treadmill exercise protocol to prevent muscle weakness, atrophy and alterations in calcium regulation in adult, old and very old rats. Adult (7-12 months), old (29-30 months) and very old (34-36 months) F344BNF(1) rats were randomly assigned to weight bearing (WB), weight bearing exercise (WBX), non-weight bearing (NWB) and non-weight bearing exercise (NWBX) groups. The WB group was considered the sedentary-control animals. NWB rats were hindlimb unweighted for 14 days. WBX and NWBX groups were exercised on a treadmill for approximately 15 min four times daily. The contractile properties [diameter, peak active force (P(0)), specific tension (P(0)/CSA)] of single myosin heavy chain type II fibers and Ca regulation [Ca(2+) dependent ATPase activity] were determined. Fiber diameter reduced by 24% in the very old rats with NWB. P(0) and P(0)/CSA declined in the young adult and very old rats with NWB. NWBX attenuated these changes in the young and very old rats. Ca(2+) dependent ATPase activity increased with treadmill exercise during non-weight bearing in the young animals. In conclusion, the treadmill exercise is beneficial in attenuating the non-weight bearing-induced changes in the individual MHC type II muscle fibers of the gastrocnemius muscle.
机译：这项研究的目的是研究跑步机运动方案对成年，成年和成年大鼠的肌肉无力，萎缩和钙调节改变的影响。将成年（7-12个月），成年（29-30个月）和非常老（34-36个月）F344BNF（1）大鼠随机分为负重（WB），负重锻炼（WBX）和非负重（NWB）和非负重锻炼（NWBX）组。 WB组被认为是久坐对照动物。对NWB大鼠后肢不加重14天。 WBX和NWBX组每天在跑步机上运动约15分钟，每次四次。确定了单个肌球蛋白重链II型纤维的收缩特性[直径，峰值活性力（P（0）），比张力（P（0）/ CSA）]和Ca调控[Ca（2+）依赖性ATPase活性] 。在非常老的NWB大鼠中，纤维直径减少了24％。 NWB的年轻成年和非常老的大鼠中P（0）和P（0）/ CSA下降。 NWBX减弱了幼鼠和非常老鼠的这些变化。 Ca（2+）依赖的ATPase活性在年轻动物的非负重过程中随着跑步机运动而增加。总之，跑步机锻炼有益于减轻腓肠肌的单个MHC II型肌肉纤维中非承重引起的变化。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号