MRSA: status and prospects for therapy? An evaluation of key papers on the topic of MRSA and antibiotic resistance.

Barrett JF

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MRSA: status and prospects for therapy? An evaluation of key papers on the topic of MRSA and antibiotic resistance.

机译：MRSA：治疗的现状和前景？对有关MRSA和抗生素耐药性主题的关键论文的评估。

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Methicillin-resistant Staphylococcus aureus (MRSA) is a serious nosocomial pathogen, and a related community-sourced MRSA is emerging. MRSA has evolved to become the major S. aureus phenotype in the hospital, emerging from just 30 to over 60% of the S. aureus population over the past 15 years. Together with its beta-lactam resistance, MRSA possesses multi-drug resistance genotype, including quinolones, macrolides and sulfonamides. MRSA has now emerged as the predominant nosocomial Gram-positive pathogen, and it has a high rate of mortality. Action must be taken to contain and eradicate MRSA through a combination of infection control and the development of novel anti-MRSA agents and vaccines.

机译：耐甲氧西林金黄色葡萄球菌（MRSA）是一种严重的医院病原体，并且相关的社区来源MRSA也正在兴起。 MRSA已发展成为医院的主要金黄色葡萄球菌表型，在过去15年中仅从30％上升到60％以上。连同其对β-内酰胺的抗性，MRSA具有多重抗药性的基因型，包括喹诺酮类，大环内酯类和磺酰胺类。 MRSA现在已经成为主要的医院革兰氏阳性病原体，并且具有很高的死亡率。必须采取行动，通过结合感染控制和开发新型抗MRSA试剂和疫苗来遏制和根除MRSA。

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《Expert opinion on therapeutic targets》 |2004年第6期|共5页
作者
Barrett JF;
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原文格式 PDF
正文语种 eng
中图分类药学;
关键词
Methicillin Resistance; Staphylococcal Infections; Staphylococcus aureus; 甲氧西林抗药性; 葡萄球菌感染; 葡萄球菌; 金黄色;

机译：Methicillin Resistance;Staphylococcal Infections;Staphylococcus aureus;甲氧西林抗药性;葡萄球菌感染;葡萄球菌;金黄色;

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1. MRSA: status and prospects for therapy? An evaluation of key papers on the topic of MRSA and antibiotic resistance. [J] . Barrett JF Expert opinion on therapeutic targets . 2004,第6期

机译：MRSA：治疗的现状和前景？对有关MRSA和抗生素耐药性主题的关键论文的评估。
2. Emergence of methicillin-resistant Staphylococcus aureus (MRSA) as a public-health threat and future directions of antibiotic therapy for MRSA infections [J] . PhytochemicalPharmacologicalandMicrobiologicalLaboratory, DepartmentofBiochemistrySaurashtraUniversity Anti-infective agents . 2012,第2期

机译：耐甲氧西林的金黄色葡萄球菌（MRSA）的出现对公共健康构成威胁，以及对MRSA感染进行抗生素治疗的未来方向
3. Review of MRSA screening and antibiotics prophylaxis in orthopaedic trauma patients; The risk of surgical site infection with inadequate antibiotic prophylaxis in patients colonized with MRSA [J] . Iqbal H. J., Ponniah N., Long S., Injury . 2017,第7期

机译：矫形外科创伤患者MRSA筛查和抗生素预防的综述; 用MRSA殖民地殖民地抗生素预防患者外科遗址感染的风险
4. Investigation into the potential of sub-lethal photodynamic antimicrobial chemotherapy (PACT) to reduce susceptibility of meticillin-resistant Staphylococcus aureus (MRSA) to antibiotics [C] . C. M. Cassidy, R. F. Donnelly, M. M. Tunney World congress of the International Photodynamic Association . 2009

机译：研究亚致死性光动力抗菌化学疗法（PACT）降低耐甲氧西林金黄色葡萄球菌（MRSA）对抗生素的敏感性
5. Discovery and biochemical evaluation of chemical probes for the study of jumonji-C domain containing histone demethylases and antibiotic resistance machinery in MRSA [D] . Podoll, Jessica Danielle 2015

机译：用于研究MRSA中含有组蛋白去甲基化酶和抗生素抗性机制的jumonji-C域的化学探针的发现和生化评估
6. Comparative Evaluation of Two PCR-Based Methods for Detection of Methicillin-Resistant Staphylococcus aureus (MRSA): Xpert MRSA Gen 3 and BD-Max MRSA XT [O] . Margaux Lepainteur, Sandrine Delattre, Sophie Cozza, 2015

机译：两种基于PCR的耐甲氧西林金黄色葡萄球菌（MRSA）检测方法的比较评估：Xpert MRSA Gen 3和BD-Max MRSA XT
7. MRSA.An advance on diagnosis and treatment.3 Actual situation of countermeasure of MRSA.3 Chemotherapy of MRSA infectious diseases. [O] . 1992

机译：MRSA.AN诊断和治疗前进.3 MRSA传染病MRSA3化疗的实际情况。
8. Impact of MRSA Decolonization Therapy on MRSA Infection and Transmission. Inclusive Project Dates: 07/01/11 - 04/30/13. [R] . A. G. Mainous 2013

机译：mRsa非殖民化治疗对mRsa感染和传播的影响。包容性项目日期：07/01/11 - 04/30/13。

MRSA: status and prospects for therapy? An evaluation of key papers on the topic of MRSA and antibiotic resistance.

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