Therapeutic targets for the treatment of hepatitis E virus infection

Kenney Scott P.; Meng Xiang-Jin

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Therapeutic targets for the treatment of hepatitis E virus infection

机译：治疗戊型肝炎病毒感染的治疗目标

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Introduction: Hepatitis E virus (HEV) is one of the most common causes of acute viral hepatitis in the world with an estimated 20 million infections per year. Although the mortality rate is < 1% among the general population, pregnant women can have a fatality rate of up to 30%. Additionally, chronic hepatitis E has increasingly become a significant clinical problem in immunocompromised individuals. Effective antivirals against HEV are needed.

机译：简介：戊型肝炎病毒（HEV）是世界上急性病毒性肝炎的最常见原因之一，估计每年感染2000万。尽管在一般人群中死亡率不到1％，但孕妇的死亡率可能高达30％。另外，慢性戊型肝炎已逐渐成为免疫功能低下个体的重要临床问题。需要针对HEV的有效抗病毒药。

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《Expert opinion on therapeutic targets》 |2015年第9期|共16页
作者
Kenney Scott P.; Meng Xiang-Jin;
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原文格式 PDF
正文语种 eng
中图分类药学;
关键词
antiviral target; antisense therapy; antiviral therapeutics; hepatitis E; hepatitis E virus; proteasome inhibitors;

机译：抗病毒靶标;反义疗法;抗病毒疗法;戊型肝炎;戊型肝炎病毒;蛋白酶体抑制剂;

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1. Therapeutic targets for the treatment of hepatitis E virus infection [J] . Kenney Scott P., Meng Xiang-Jin Expert opinion on therapeutic targets . 2015,第9期

机译：治疗戊型肝炎病毒感染的治疗目标
2. Frequency and Associated Risk Factors of Hepatitis B Virus and Hepatitis C Virus Infections in Children at a Hepatitis Prevention and Treatment Clinic in Lahore, Pakistan [J] . Iqtadar Seerat, Humaira Mushtaq, Memona Rafiq, Cureus. . 2020,第5期

机译：巴基斯坦拉合尔肝炎预防和治疗诊所儿童乙型肝炎病毒和丙型肝炎病毒感染的频率和相关危险因素
3. Is there a meaningful serum hepatitis B virus DNA cutoff level for therapeutic decisions in hepatitis B e antigen-negative chronic hepatitis B virus infection? [J] . Papatheodoridis GV, Manesis EK, Manolakopoulos S, Hepatology: Official Journal of the American Association for the Study of Liver Diseases . 2008,第5期

机译：是否存在有意义的血清B型肝炎病毒DNA截止水平，可用于治疗B型肝炎e抗原阴性的慢性B型肝炎病毒感染？
4. Hyaluronic Acid - Gold Nanoparticle/Interferon a Complex for Targeted Treatment of Hepatitis C Virus Infection [C] . Sei Kwang Hahn, Min-Young Lee, Jeong-A Yang, Society for Biomaterials annual meeting and exposition . 2013

机译：透明质酸-金纳米颗粒/干扰素复合物，用于靶向治疗丙型肝炎病毒感染
5. Impacts of Hepatitis C Virus Infection Treatment for Patients in Treatment for Opioid Use Disorder [D] . Severe, Brooke. 2019

机译：丙型肝炎病毒感染治疗对患者的影响对阿片类药物使用障碍的影响
6. Hepatocyte-targeted RNAi Therapeutics for the Treatment of Chronic Hepatitis B Virus Infection [O] . Christine I Wooddell, David B Rozema, Markus Hossbach, 2013

机译：靶向肝细胞的RNAi治疗慢性乙型肝炎病毒感染的治疗
7. Clinical testing of a dendritic cell targeted therapeutic vaccine in patients with chronic hepatitis C virus infection [O] . Aintzane Zabaleta, Delia D'Avola, Itziar Echeverria, 2015

机译：针对慢性丙型肝炎病毒感染患者的树突状细胞靶向治疗性疫苗的临床试验

Therapeutic targets for the treatment of hepatitis E virus infection

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