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首页> 外文期刊>Expert review of vaccines >A routine infant schedule versus an older infant/toddler schedule for Neisseria meningitidis vaccination: what do experience and reason tell us?
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A routine infant schedule versus an older infant/toddler schedule for Neisseria meningitidis vaccination: what do experience and reason tell us?

机译：脑膜炎奈瑟氏菌疫苗接种的常规婴儿时间表与较大的婴儿/幼儿时间表：经验和原因告诉我们什么？

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摘要

Prior to universal infant immunization programs that focused on infants in the first 6 months of life, the three bacterial pathogens responsible for most cases of bacterial meningitis in the USA were Haemophilus influenzae type b (Hib), Streptococcus pneumoniae (pneumococ-cus) and Neisseria meningitidis (meningo-coccus) [2-5]. Beginning in the early and mid-1990s, routine infant immunization with Hib conjugate vaccines and the hep-tavalent pneumococcal conjugate vaccine began to dramatically reduce the incidence of invasive disease caused by these encapsulated bacterial pathogens. With the successes of universal Hib and pneumococcal immunization programs, and the consequent reduction in morbidity and mortality due to these two organisms, the remaining morbidity and mortality due to the one remaining encapsulated organism in infants were highlighted.
机译：在针对婴儿出生后头6个月的婴儿进行通用婴儿免疫计划之前，美国大多数细菌性脑膜炎病例的三种细菌病原体分别为b型流感嗜血杆菌（Hib），肺炎链球菌（肺炎球菌）和奈瑟氏球菌。脑膜炎球菌（脑膜炎球菌）[2-5]。从1990年代初期和中期开始，用Hib结合疫苗和七价肺炎球菌结合疫苗进行常规的婴儿免疫开始显着降低由这些包囊的细菌病原体引起的侵袭性疾病的发生率。随着普遍的Hib和肺炎球菌免疫接种计划的成功，以及由于这两种生物导致的发病率和死亡率的降低，突出了婴儿中仅存的一种包囊生物导致的发病率和死亡率。

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