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首页> 外文期刊>Gastrointestinal Endoscopy >In praise of folly: the Erasmus score for intestinal metaplasia.
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In praise of folly: the Erasmus score for intestinal metaplasia.

机译：愚蠢的称赞：伊拉斯mus小肠化生评分。

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摘要

There are 3 common questions that gastroenterologists pose to pathologists regarding gastric atrophy or intestinal metaplasia: "How do we assess cancer risk?" "How can we decide which patients should have surveillance endos-copy?" and "How frequently do we need to survey?" Because, as pathologists, we have no guidelines, we answer with opinions rather than evidence. A wealth of epidemio-logic data indicate that extent, intensity, and distribution patterns of gastric inflammation, atrophy, and intestinal metaplasia are consistently related to the incidence of gastric cancer in a population. However, at an individual patient's level, pathologists lack the instruments to translate the histopathologic information into a standardized report that would convey comprehensive information on the gastric condition and provide a reliable assessment of cancer risk. In 2005, we proposed a systematic approach, based on the biopsy protocol of the updated Sydney System, for reporting the phenotypes of chronic gastritis in terms of grading and staging. Grading was intended to express the cumulative intensity of the inflammatory components, whereas staging would express the anatomical extent of the atrophic-metaplastic changes related to cancer risk. When the proposal was submitted to a clinical gastroenter-ology journal (not Gastrointestinal Endoscopy.), one of the anonymous reviewers made the following observations:
机译：肠胃科医生向病理学家提出有关胃萎缩或肠化生的三个常见问题：“我们如何评估癌症风险？” “我们如何确定应该对哪些患者进行内窥镜检查？”和“我们需要多久进行一次调查？”因为作为病理学家，我们没有指导方针，所以我们以观点而不是证据来回答。大量的流行病学数据表明，胃炎症，萎缩和肠化生的程度，强度和分布方式与人群中胃癌的发生率始终相关。但是，在单个患者的水平上，病理学家缺乏将组织病理学信息转换为标准化报告的工具，该报告无法传达有关胃部疾病的全面信息并提供可靠的癌症风险评估。 2005年，我们根据更新后的悉尼系统的活检协议提出了一种系统的方法，用于根据分级和分期报告慢性胃炎的表型。分级旨在表达炎性成分的累积强度，而分期将表达与癌症风险相关的萎缩性间质改变的解剖范围。当该提案提交给临床胃肠病学杂志（非胃肠道内窥镜检查）时，一位匿名评论者发表了以下意见：

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