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首页> 外文期刊>Gastrointestinal Endoscopy >Capsule endoscopy performed across the pediatric age range: indications, incomplete studies, and utility in management of inflammatory bowel disease.
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Capsule endoscopy performed across the pediatric age range: indications, incomplete studies, and utility in management of inflammatory bowel disease.

机译：胶囊内窥镜检查在儿童年龄范围内进行：适应症，研究不完整以及在炎症性肠病治疗中的实用性。

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BACKGROUND: Capsule endoscopy (CE) is used increasingly to evaluate the small bowel in children. An upper GI series is recommended before CE to evaluate the risk of obstruction. Despite normal findings on an upper GI series, CE may still be incomplete. Although large adult studies have demonstrated the safety and diagnostic yield of CE, similar pediatric studies have not been available. OBJECTIVE: To identify factors associated with incomplete studies and the diagnostic yield in pediatric patients. DESIGN: Retrospective review of consecutive CE studies from February 2005 through June 2008. SETTING: Large tertiary children's hospital. PATIENTS: A total of 123 CE studies in 117 patients; median age 12.9 years (range 0.8-22.4 years). MAIN OUTCOME MEASUREMENTS: Demographic information, indication, placement technique, pre-CE imaging results, and cecal completion status were recorded. Risk factors were analyzed with bivariate and multivariate regression analysis. RESULTS: There were 27 (22%) incomplete studies; of these, there were normal pre-CE radiologic study findings in 12 (44%), and findings requiring medical, endoscopic, or operative intervention in 6. Of the 117 patients, CE produced a new diagnosis in 21 (18%). Abnormal findings on previous imaging (odds ratio [OR] 3.0; 95% CI, 1.2-8.0), endoscopic placement (OR 3.1; 95% CI, 1.1-8.4), and female sex (OR 3.3; 95% CI, 1.2-9.4) were associated with incomplete studies. LIMITATIONS: Retrospective, incomplete follow-up. CONCLUSIONS: CE may be performed in children as small as 11.5 kg, with 18% yield in all studies, and 28% in pediatric known inflammatory bowel disease. Capsule retention requiring retrieval did not pose life-threatening risk in our series, and CE may be used to identify disease-associated small-bowel stenosis.
机译：背景：胶囊内窥镜检查（CE）越来越多地用于评估儿童的小肠。建议在CE之前使用较高的GI系列评估梗阻的风险。尽管在较高的GI系列上有正常发现，CE可能仍不完整。尽管大型的成人研究证明了CE的安全性和诊断率，但尚无类似的儿科研究。目的：确定与未完成研究有关的因素以及小儿患者的诊断率。设计：从2005年2月至2008年6月，对连续性CE研究进行回顾性回顾。地点：大型三级儿童医院。患者：117位患者共进行了123项CE研究;中位年龄12.9岁（范围0.8-22.4岁）。主要观察指标：记录人口统计学信息，适应症，放置技术，CE前影像学检查结果和盲肠完成状态。风险因素通过二元和多元回归分析进行分析。结果：有27项（22％）未完成的研究;在这些患者中，有12例（44％）处于CE之前的放射学检查结果正常，而6例需要进行医学，内镜或手术干预的结果在117例患者中，有21例（18％）出现了CE的新诊断。先前影像学的异常发现（几率[OR] 3.0; 95％CI，1.2-8.0），内镜放置（OR 3.1; 95％CI，1.1-8.4）和女性（OR 3.3; 95％CI，1.2- 9.4）与不完整的研究有关。局限性：回顾性，不完整的随访。结论：CE可以在小至11.5kg的儿童中进行，在所有研究中产率为18％，在儿科已知的炎症性肠病中为28％。在我们的系列中，需要保留的胶囊保留不会威胁生命，因此CE可以用于识别与疾病相关的小肠狭窄。

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