Decreased expression of human heat shock protein 70 in the endometria and pathological lesions of women with adenomyosis and uterine myoma after GnRH agonist therapy

Khan Khaleque N.; Kitajima Michio; Hiraki Koichi; Fujishita Akira; Nakashima Masahiro; Masuzaki Hideaki

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Decreased expression of human heat shock protein 70 in the endometria and pathological lesions of women with adenomyosis and uterine myoma after GnRH agonist therapy

机译：GnRH激动剂治疗后子宫腺肌病和子宫肌瘤妇女子宫内膜和病理病变中人热休克蛋白70表达降低

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Objective: A prominent stress reaction in the pelvis of women with endometriosis and the role of human heat shock protein 70 (HSP70) in inflammation and the growth of endometriosis has been recently demonstrated. We report here expression of HSP70 in tissues derived from GnRH agonist (GnRHa)untreated and -treated women with adenomyosis and uterine myoma.

机译：目的：最近已证明子宫内膜异位症妇女的骨盆中有明显的应激反应，以及人类热休克蛋白70（HSP70）在炎症和子宫内膜异位症生长中的作用。我们在这里报告了在患有腺肌病和子宫肌瘤的未治疗和已治疗妇女的GnRH激动剂（GnRHa）衍生的组织中HSP70的表达。

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来源
《European Journal of Obstetrics, Gynecology and Reproductive Biology: An International Journal》 |2015年第null期|共8页
作者
Khan Khaleque N.; Kitajima Michio; Hiraki Koichi; Fujishita Akira; Nakashima Masahiro; Masuzaki Hideaki;
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正文语种 eng
中图分类妇产科学;
关键词
Adenomyosis; Uterine myoma; HSP70; Inflammation; GnRHa;

机译：子宫腺肌病;子宫肌瘤;HSP70;炎症;GnRHa;

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1. Decreased expression of human heat shock protein 70 in the endometria and pathological lesions of women with adenomyosis and uterine myoma after GnRH agonist therapy [J] . Khan Khaleque N., Kitajima Michio, Hiraki Koichi, European Journal of Obstetrics, Gynecology and Reproductive Biology: An International Journal . 2015,第Null期

机译：GnRH激动剂治疗后子宫腺肌病和子宫肌瘤妇女子宫内膜和病理病变中人热休克蛋白70表达降低
2. Cell proliferation effect of GnRH agonist on pathological lesions of women with endometriosis, adenomyosis and uterine myoma. [J] . Khan KN, Kitajima M, Hiraki K, Human Reproduction . 2010,第11期

机译：GnRH激动剂对子宫内膜异位症，子宫腺肌病和子宫肌瘤妇女病理病变的细胞增殖作用。
3. Cell proliferation effect of GnRH agonist on pathological lesions of women with endometriosis, adenomyosis and uterine myoma [J] . Khaleque Newaz Khan, Michio Kitajima, Koichi Hiraki, Human Reproduction . 2010,第11期

机译：GnRH激动剂对子宫内膜异位症，子宫腺肌病和子宫肌瘤女性病变的细胞增殖作用
4. Etiological expression of heat shock protein 70 (HSP70) in human endothelial cells with hemodynamic shear stress [C] . Jun Keun Chang, Dong Chul Han ASME International Mechanical Engineering Congress and Exposition . 1999

机译：具有血流动力学剪切应力的人内皮细胞中热休克蛋白70（HSP70）的病因表达
5. The expression of heat shock protein 70, heat shock protein 90 and heat shock factor 1 within the bovine midcycle corpus luteum after stimulation with temperature in vitro and PGF2alpha in vitro and in vivo. [D] . Kopka, Melissa N. 2006

机译：热激蛋白70，热激蛋白90和热激因子1在体外温度和体外及体内PGF2α刺激后在牛黄体中体中的表达。
6. Enhanced expression of heat shock protein 70 (hsp70) and heat shock factor 1 (HSF1) activation in rheumatoid arthritis synovial tissue. Differential regulation of hsp70 expression and hsf1 activation in synovial fibroblasts by proinflammatory cytokines shear stress and antiinflammatory drugs. [O] . G Schett, K Redlich, Q Xu, 1998

机译：类风湿关节炎滑膜组织中热休克蛋白70（hsp70）和热休克因子1（HSF1）激活的增强表达。促炎细胞因子剪切应力和抗炎药对滑膜成纤维细胞中hsp70表达和hsf1激活的差异调节。
7. Decreased expression of human heat shock protein 70 in the endometria and pathological lesions of women with adenomyosis and uterine myoma after GnRH agonist therapy [O] . Khan Khaleque Newaz, Kitajima Michio, Hiraki Koichi, 2015

机译：GnRH激动剂治疗后子宫内膜异位症和子宫肌瘤患者子宫内膜和病理性病变中人热休克蛋白70的表达下降

Decreased expression of human heat shock protein 70 in the endometria and pathological lesions of women with adenomyosis and uterine myoma after GnRH agonist therapy

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