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Current views on interferon therapy for HIV

机译:艾滋病毒干扰素治疗的最新观点

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Introduction: Knowledge of IFN-antiviral activity against HIV infection dates from the first years of the AIDS epidemic. Recombinant IFN had an inhibitory effect on HIV and was not toxic to peripheral blood mononuclear cells (PBMC), and this finding was the basis for the design of clinical trials that evaluated the potential role of IFN-alpha as an inhibitor of HIV replication.
机译:简介:IFN-抗病毒活性对HIV感染的知识始于AIDS流行的头几年。重组IFN对HIV具有抑制作用,对外周血单核细胞(PBMC)无毒,这一发现是临床试验设计的基础,该临床试验评估了IFN-α作为HIV复制抑制剂的潜在作用。

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