Ofatumumab in the treatment of non-Hodgkin's lymphomas

Karlin Lionel; Coiffier Bertrand

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Ofatumumab in the treatment of non-Hodgkin's lymphomas

机译：Ofatumumab治疗非霍奇金淋巴瘤

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Introduction: Ofatumumab is a second-generation humanized monoclonal antibody targeting CD20 registered for the treatment of patients with relapsing/refractory chronic lymphocytic leukemia. This review will describe the activity of ofatumumab in patients with CD20 B-cell lymphomas.

机译：简介：Ofatumumab是靶向CD20的第二代人源化单克隆抗体，已注册用于治疗复发/难治性慢性淋巴细胞性白血病的患者。这篇综述将描述ofatumumab在CD20 B细胞淋巴瘤患者中的活性。

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《Expert opinion on biological therapy》 |2015年第7期|共7页
作者
Karlin Lionel; Coiffier Bertrand;
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原文格式 PDF
正文语种 eng
中图分类治疗学;
关键词
diffuse large B-cell lymphoma; follicular lymphoma; ofatumumab;

机译：弥漫性大B细胞淋巴瘤;滤泡性淋巴瘤;ofatumumab;

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专利

1. Ofatumumab in the treatment of non-Hodgkin's lymphomas [J] . Karlin Lionel, Coiffier Bertrand Expert opinion on biological therapy . 2015,第7期

机译：Ofatumumab治疗非霍奇金淋巴瘤
2. Results of the Primary Analysis of Complement A plus B: A Phase III Study of Ofatumumab in Combination with Bendamustine Versus Bendamustine Alone in Patients with Indolent Non-Hodgkin's Lymphoma That Is Unresponsive Following Rituximab or Rituximab-Containing Regimen [J] . Rummel Mathias J., Janssens Ann, MacDonald David, Blood: The Journal of the American Society of Hematology . 2018,第NovaelaTreatmentAppr期

机译：补体A PLUS B的初步分析结果：单独与苯妥汀与苯妥甘蔗丝蛋白相结合的III类研究，其单独在惰性非霍奇金淋巴瘤患者中，含有鲁妥昔单抗或含人民肢体方案的淋巴瘤无响应
3. Results of a phase II study of bendamustine and ofatumumab in untreated indolent B cell non-Hodgkin's lymphoma [J] . Czuczman Myron S., Kahanic Stephen, Forero Andres, Annals of hematology . 2015,第4期

机译：苯达莫司汀和ofatumumab在未经治疗的惰性B细胞非霍奇金淋巴瘤的II期研究中的结果
4. Development of Single Domain Antibodies for Diagnosis and Treatment of Naturally Occurring Canine Lymphoma: An Animal Model for Human Non-Hodgkin Lymphoma [C] . Joana Dias, Solange Gil, Belmira Carrapico, PEGS . 2015

机译：天然犬淋巴瘤诊断和治疗单结构域抗体的发展：人非霍奇金淋巴瘤的动物模型
5. Targeting the translational machinery as a novel treatment strategy for non-Hodgkin lymphoma. [D] . Hagner, Patrick R. 2010

机译：针对非霍奇金淋巴瘤的新型治疗策略，以翻译机制为目标。
6. Transformed large B-cell lymphoma in rituximab-allergic patient with chronic lymphocytic leukemia after allogeneic stem cell transplant: successful treatment with ofatumumab [O] . Michael A. Linden, Veronika Bachanova, Zohar Sachs, -1

机译：利妥昔单抗过敏的患者异基因造血干细胞移植后慢性淋巴细胞性白血病转化的大B细胞淋巴瘤：用奥法木单抗治疗成功
7. Results of a prospective phase II trial with ofatumumab as part of reduced intensity conditioning regimen in high-risk non-Hodgkin B lymphoma patients: A GELTAMO trial [O] . M. Cabrero, L. Lopez-Corral, F. de la Cruz, 2017

机译：随着高风险非霍奇金B淋巴瘤患者中强度调理方案的一部分，幼儿园药物审判试验的潜在期II试验结果：GELTAMO试验

Ofatumumab in the treatment of non-Hodgkin's lymphomas

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