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首页> 外文期刊>Genes to cells : >The reaction-diffusion system: a mechanism for autonomous pattern formation in the animal skin.
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The reaction-diffusion system: a mechanism for autonomous pattern formation in the animal skin.

机译：反应扩散系统：一种在动物皮肤中自主形成图案的机制。

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How do animals acquire their various skin patterns? Although this question may seem easy, in fact it is very difficult to answer. The problem is that most animals have no related structures under the skin; therefore, the skin cells must form the patterns without the support of a prepattern. Recent progress in developmental biology has identified various molecular mechanisms that function in setting the positional information needed for the correct formation of body structure. None of these can explain how skin pattern is formed, however, because all such molecular mechanisms depend on the existing structure of the embryo. Although little is known about the underlying molecular mechanism, many theoretical studies suggest that the skin patterns of animals form through a reaction-diffusion system-a putative 'wave' of chemical reactions that can generate periodic patterns in the field. This idea had remained unaccepted for a long time, but recent findings on the skin patterns of fish have proved that such waves do exist in the animal body. In this review, we explain briefly the principles of the reaction-diffusion mechanism and summarize the recent progress made in this area.
机译：动物如何获得各种皮肤图案？尽管这个问题看似容易，但实际上很难回答。问题在于大多数动物的皮下都没有相关的结构。因此，皮肤细胞必须在没有预图案支持的情况下形成图案。发展生物学的最新进展已经确定了各种分子机制，这些分子机制在设定正确形成身体结构所需的位置信息中起作用。但是，所有这些分子机理都不能解释如何形成皮肤图案，因为所有这些分子机制都取决于胚胎的现有结构。尽管对潜在的分子机制知之甚少，但许多理论研究表明，动物的皮肤模式是通过反应扩散系统形成的，这是化学反应的“波”，可以在野外产生周期性模式。这种想法很久以来一直未被接受，但是最近对鱼皮肤模式的发现已经证明这种波确实存在于动物体内。在这篇综述中，我们简要解释了反应扩散机理的原理，并总结了该领域的最新进展。

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