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首页> 外文期刊>European addiction research >Office-based treatment in opioid dependence: a critical survey of prescription practices for opioid maintenance medications and concomitant benzodiazepines in Vienna, Austria.
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Office-based treatment in opioid dependence: a critical survey of prescription practices for opioid maintenance medications and concomitant benzodiazepines in Vienna, Austria.

机译：基于办公室的阿片类药物依赖性治疗：对奥地利维也纳的阿片类药物维持药物和伴随的苯二氮类药物处方实践的重要调查。

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BACKGROUND: The success of maintenance treatment for opioid dependence in office-based settings is influenced by the extent of treatment coverage, the availability of effective medications and the capacity of general practitioners to prescribe opioids in adequate doses with a minimum of concomitant benzodiazepine prescriptions. METHODS: This study compares prescriptions for opioid maintenance and concomitant benzodiazepine from Viennese physicians in 2002 and 2005 using health insurance prescription records (n = 30,309). RESULTS: Between 2002 and 2005, the number of patients prescribed opioids more than doubled (ratio 1:2.3), slow-release oral morphine replaced methadone as the most frequently prescribed medication (57.1 vs. 23.4%; buprenorphine 19.5%), and the ratio of benzodiazepine to opioid prescriptions significantly declined (0.76:1 vs. 0.42:1). Many patients were prescribed concomitant benzodiazepines (27%), in some cases from a secondary physician. CONCLUSION: Increased utilization of opioid medications in office-based settings will facilitate better treatment coverage. However, safeguards are necessary to ensure that general practitioners have sufficient training and support to safely and appropriately provide treatment, including the reduction in concomitant benzodiazepine use.
机译：背景：在办公室环境中维持阿片类药物依赖治疗的成功与否，取决于治疗覆盖范围，有效药物的可获得性以及全科医生开具足够剂量的阿片类药物并使用最少的苯二氮卓类处方的能力。方法：本研究使用健康保险处方记录（n = 30,309），比较了2002年和2005年来自维也纳医师的阿片类药物维持及伴随苯二氮卓类药物的处方。结果：从2002年到2005年，开处方阿片类药物的患者人数增加了一倍以上（比率1：2.3），缓释口服吗啡替代了美沙酮作为最常用的处方药物（57.1比23.4％;丁丙诺啡19.5％），苯二氮卓类药物与阿片类药物处方的比例显着下降（0.76：1比0.42：1）。许多患者被处方同时服用苯二氮卓类药物（占27％），某些情况下是由二级医师开具的。结论：在办公室环境中增加类阿片药物的利用率将促进更好的治疗覆盖率。但是，必须采取保障措施，以确保全科医生获得足够的培训和支持，以安全适当地提供治疗，包括减少并用苯二氮卓类药物。

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