...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>European archives of oto-rhino-laryngology: Official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) >Free-flap reconstruction for laryngeal preservation after partial laryngectomy in patients with extended tumors of the oropharynx and hypopharynx.
【24h】

Free-flap reconstruction for laryngeal preservation after partial laryngectomy in patients with extended tumors of the oropharynx and hypopharynx.

机译：口咽和下咽部肿瘤扩大的患者，在部分喉切除术后自由瓣重建以保留喉镜。

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Partial laryngeal resection often results in major aspiration problems, making larynx preservation during surgical removal of tumors of the oropharynx and hypopharynx impossible. However, free flaps can be used to reconstruct perilaryngeal tissue, thus preserving the larynx and ensuring a better quality of life for patients. We present the results of forearm free-flap reconstruction of the supraglottis in 22 patients who underwent resections of extended squamous cell carcinomas of the oropharynx and hypopharynx. A total of 9 patients had T3 lesions and 13 had T4 lesions. All patients were additionally treated with radiation therapy alone (to 70 Gy) or in combination with chemotherapy (Cisplatin; 5-fluorouracil). The mean follow-up was 2.4 years. In four patients, tracheostomy could be closed. Five patients suffered from severe aspiration, one of whom had to undergo a laryngectomy. Six patients had mild aspiration and 7 patients had no aspiration, but extensive edema made decanulation impossible. A total of 13 patients were free of disease, 4 patients died of disease, 1 patient died as the result of a second primary cancer and 1 patient died of other causes. Three patients are alive with persistent tumor. Although the majority of patients experienced a better quality of life as a result of larynx preservation, aspiration has remained a problem following treatment.
机译：喉部分切除术通常会导致严重的抽吸问题，使得在手术切除口咽和下咽肿瘤时无法保留喉头。但是，游离皮瓣可用于重建唇周组织，从而保留喉部并确保患者更好的生活质量。我们介绍了22例接受口咽和下咽的鳞状鳞癌切除术的患者的上舌前臂自由瓣重建的结果。共有9例患者患有T3病变，而13例患有T4病变。所有患者均单独接受放射治疗（至70 Gy）或联合化疗（顺铂; 5-氟尿嘧啶）。平均随访时间为2。4年。在四名患者中，气管切开术可以关闭。五名患者有严重的误吸，其中一名必须进行喉切除术。 6例患者有轻度抽吸，7例患者无抽吸，但是广泛的水肿使得无法进行去气。共有13名患者无病，4名患者死于疾病，1名患者死于第二次原发性癌症，1名患者死于其他原因。 3例患者患有持续性肿瘤。尽管大多数患者由于保留了喉头而生活质量得到改善，但治疗后仍存在抽吸困难。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号