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Streptococcus pneumoniae Genome Database (SPGDB): A database for strain specific comparative analysis of Streptococcus pneumoniae genes and proteins

机译：肺炎链球菌基因组数据库（SPGDB）：用于对肺炎链球菌基因和蛋白质进行菌株特异性比较分析的数据库

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摘要

Streptococcus pneumoniae causes pneumonia, septicemia and meningitis. S. pneumoniae is responsible for significant mortality both in children and in the elderly. In recent years, the whole genome sequencing of various S. pneumoniae strains have increased manifold and there is an urgent need to provide organism specific annotations to the scientific community. This prompted us to develop the Streptococcus pneumoniae Genome Database (SPGDB) to integrate and analyze the completely sequenced and available S. pneumoniae genome sequences. Further, links to several tools are provided to compare the pool of gene and protein sequences, and proteins structure across different strains of S. pneumoniae. SPGDB aids in the analysis of phenotypic variations as well as to perform extensive genomics and evolutionary studies with reference to S. pneumoniae. (C) 2014 Elsevier Inc. All rights reserved.
机译：肺炎链球菌引起肺炎，败血病和脑膜炎。肺炎链球菌是导致儿童和老年人死亡的重要原因。近年来，各种肺炎链球菌菌株的全基因组测序已增加了多方面的需求，迫切需要向科学界提供生物体特定的注释。这促使我们开发肺炎链球菌基因组数据库（SPGDB），以整合和分析完全测序且可用的肺炎链球菌基因组序列。此外，提供了与几种工具的链接，以比较基因和蛋白质序列库，以及跨肺炎链球菌不同菌株的蛋白质结构。 SPGDB有助于分析表型变异以及参考肺炎链球菌进行广泛的基因组学和进化研究。 （C）2014 Elsevier Inc.保留所有权利。

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