...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Gait & posture >Identification of the neural component of torque during manually-applied spasticity assessments in children with cerebral palsy
【24h】

Identification of the neural component of torque during manually-applied spasticity assessments in children with cerebral palsy

机译：在脑瘫患儿进行手动痉挛评估时确定扭矩的神经成分

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Clinical assessment of spasticity is compromised by the difficulty to distinguish neural from non-neural components of increased joint torque. Quantifying the contributions of each of these components is crucial to optimize the selection of anti-spasticity treatments such as botulinum toxin (BTX). The aim of this study was to compare different biomechanical parameters that quantify the neural contribution to ankle joint torque measured during manually-applied passive stretches to the gastrocsoleus in children with spastic cerebral palsy (CP). The gastrocsoleus of 53 children with CP (10.9. ±. 3.7. y; females n= 14; bilateral/unilateral involvement n= 28/25; Gross Motor Functional Classification Score I-IV) and 10 age-matched typically developing (TD) children were assessed using a manually-applied, instrumented spasticity assessment. Joint angle characteristics, root mean square electromyography and joint torque were simultaneously recorded during passive stretches at increasing velocities. From the CP cohort, 10 muscles were re-assessed for between-session reliability and 19 muscles were re-assessed 6 weeks post-BTX. A parameter related to mechanical work, containing both neural and non-neural components, was compared to newly developed parameters that were based on the modeling of passive stiffness and viscosity. The difference between modeled and measured response provided a quantification of the neural component. Both types of parameters were reliable (ICC. >. 0.95) and distinguished TD from spastic muscles (p<. 0.001). However, only the newly developed parameters significantly decreased post-BTX (p= 0.012). Identifying the neural and non-neural contributions to increased joint torque allows for the development of individually tailored tone management.
机译：痉挛的临床评估因难以区分关节扭矩增加的神经和非神经成分而受到影响。量化每个成分的贡献对于优化抗痉挛治疗方法（如肉毒杆菌毒素（BTX））的选择至关重要。这项研究的目的是比较不同的生物力学参数，这些参数量化了对痉挛性脑瘫（CP）患儿进行手动被动拉伸至腓肠肌期间对踝关节扭矩的神经贡献。 53例CP患儿的胃大便（10.9。±。3.7。y;女性n = 14;双边/单侧受累n = 28/25;总运动功能分类得分I-IV）和10个年龄相仿的典型发育儿童（TD）使用手动应用的，仪器化的痉挛评估对儿童进行评估。关节角度特征，均方根肌电图和关节扭矩在被动拉伸过程中以增加的速度同时记录。在CP队列中，BTX后6周重新评估了10块肌肉的会话间可靠性，并重新评估了19块肌肉。将与机械功相关的参数（包含神经和非神经成分）与基于被动刚度和粘度建模的新开发参数进行了比较。建模响应与测量响应之间的差异提供了神经成分的量化。两种类型的参数都是可靠的（ICC> 0.95），并且将TD与痉挛性肌肉区分开（p <0.001）。但是，只有新开发的参数在BTX之后显着降低（p = 0.012）。识别神经和非神经对增加关节扭矩的贡献可以开发出个性化的音调管理。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号