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首页> 外文期刊>Gait & posture >Functional correlates of gait and balance difficulty in essential tremor: Balance confidence, near misses and falls
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Functional correlates of gait and balance difficulty in essential tremor: Balance confidence, near misses and falls

机译：步态的功能相关性和基本震颤的平衡困难：平衡信心，未命中和跌倒

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Background: Although a mild objective abnormality of gait and balance has been observed in essential tremor (ET) cases in research settings, the clinical significance of this finding for patients is far from clear. In this study, we assessed whether ET patients subjectively experience more gait difficulty, more falls or near misses than controls. Methods: Activities-specific Balance Confidence (ABC) scores were obtained in 59 ET cases (15 with head tremor and 44 without head tremor) and 82 controls enrolled in a clinical-epidemiological study. Results: ABC scores were lower in ET cases than controls (61.8. ±. 27.7 vs. 70.3. ±. 28.1, p= 0.035) of similar age (71.2. ±. 14.6 years vs. 71. 6. ±. 0.8 years), indicating significantly lower balance confidence in cases. The lowest scores (51.4. ±. 26.9) were observed in cases with head tremor (p= 0.02). Near misses in the past year were the highest in cases with head tremor (67.3. ±. 112.1) and lowest in controls (6.1. ±. 33.3, p= 0.008). The proportion who had had ≥5 near misses or falls in the past year was 11 (13.4%) for controls, 8 (18.2%) for cases without head tremor and 6 (40.0%) for cases with head tremor (p= 0.048). For the ABC score, we created a receiver operating curve (ROC) curve and optimal cut-off score to differentiate between our two most different groups, namely, ET with head tremor and controls. Using this cut-off (≤67), sensitivity and specificity were moderate. Conclusions: ET patients experience a loss of confidence in balance. The subgroup of patients with head tremor experienced the most gait and balance difficulty, with nearly one-in-two having had multiple near misses or falls during the previous year.
机译：背景：尽管在研究环境中的原发性震颤（ET）病例中观察到了轻微的步态和平衡客观异常，但这一发现对患者的临床意义尚不清楚。在这项研究中，我们评估了ET患者是否比对照组主观上有更多的步态困难，更多跌倒或接近失误。方法：对59例ET患者（15例发生头部震颤，44例不发生头部震颤）和82名对照进行了临床流行病学研究，获得了活动特异性平衡信心（ABC）评分。结果：ET患者的ABC评分低于同年龄（71.2。±。14.6岁vs. 71. 6.±。0.8岁）的对照组（61.8。±。27.7 vs. 70.3。±。28.1，p = 0.035）。 ，表明案例中的余额置信度大大降低。发生头部震颤的患者得分最低（51.4±26.9）（p = 0.02）。在过去的一年中，发生头部震颤的几率最高（67.3。±。112.1），而在对照组中最低（6.1。±。33.3，p = 0.008）。在过去的一年中，失控或跌倒≥5的比例为对照组：11（13.4％），无震颤病例为8（18.2％），有震颤病例为6（40.0％）（p = 0.048） 。对于ABC分数，我们创建了一个接收器操作曲线（ROC）曲线和最佳截止分数，以区分两个最不同的组，即具有头部震颤的ET和对照组。使用该临界值（≤67），敏感性和特异性适中。结论：ET患者经历失去对平衡的信心。患有头部震颤的患者亚组的步态和平衡困难最大，在上一年中，几乎有二分之一的患者多次失误或跌倒。

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