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首页> 外文期刊>Genetics in medicine >Family history and perceptions about risk and prevention for chronic diseases in primary care: a report from the family healthware impact trial.
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Family history and perceptions about risk and prevention for chronic diseases in primary care: a report from the family healthware impact trial.

机译：家族病史和对初级保健中慢性病风险和预防的认识：家庭保健产品影响试验的报告。

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PURPOSE: To determine whether family medical history as a risk factor for six common diseases is related to patients' perceptions of risk, worry, and control over getting these diseases. METHODS: We used data from the cluster-randomized, controlled Family Healthware Impact Trial (FHITr). At baseline, healthy primary care patients reported their perceptions about coronary heart disease, stroke, diabetes, and breast, ovarian, and colon cancers. Immediately afterward, intervention group participants used Family Healthware to record family medical history; this web-based tool stratified familial disease risks. Multivariate and multilevel regression analyses measured the association between familial risk and patient perceptions for each disease, controlling for personal health and demographics. RESULTS: For the 2330 participants who used Family Healthware immediately after providing baseline data, perceived risk and worry for each disease were strongly associated with family history risk, adjusting for personal risk factors. The magnitude of the effect of family history on perceived risk ranged from 0.35 standard deviation for ovarian cancer to 1.12 standard deviations for colon cancer. Family history was not related to perceived control over developing diseases. Risk perceptions seemed optimistically biased, with 48-79% of participants with increased familial risk for diseases reporting that they were at average risk or below. CONCLUSIONS: Participants' ratings of their risk for developing common diseases, before feedback on familial risk, parallels but is often lower than their calculated risk based on family history. Having a family history of a disease increases its salience and does not change one's perceived ability to prevent the disease.
机译：目的：确定家族病史作为六种常见疾病的危险因素是否与患者对风险，忧虑以及对控制这些疾病的控制感相关。方法：我们使用来自集群随机对照家庭健康软件影响试验（FHITr）的数据。在基线时，健康的初级保健患者报告了他们对冠心病，中风，糖尿病以及乳腺癌，卵巢癌和结肠癌的看法。随后，干预小组的参与者立即使用家庭保健软件记录家庭病史。这个基于网络的工具将家族性疾病的风险分层。多变量和多层次回归分析测量了每种疾病的家族风险与患者知觉之间的关联，控制了个人健康和人口统计。结果：对于提供基线数据后立即使用家庭保健软件的2330名参与者，每种疾病的感知风险和忧虑与家族病史风险密切相关，并根据个人风险因素进行了调整。家族史对感知风险的影响范围从卵巢癌的0.35标准差到结肠癌的1.12标准差不等。家族史与对疾病的控制感无关。风险认知似乎是乐观的，有48-79％的参与者患有家族性疾病的风险增高，表明他们处于中等风险或更低。结论：在对家族风险的反馈之前，参与者对发展为常见疾病的风险的评分与之相似，但通常低于根据家族史计算得出的风险。具有某种疾病的家族史会增加其显着性，并且不会改变人们预防该疾病的能力。

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