• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Genetics in medicine >Clinical utility of family history for cancer screening and referral in primary care: a report from the Family Healthware Impact Trial.
【24h】

Clinical utility of family history for cancer screening and referral in primary care: a report from the Family Healthware Impact Trial.

机译：家族病史在癌症筛查和初级保健转诊中的临床应用：《家庭保健软件影响试验》的一份报告。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

PURPOSE: To assess the effectiveness of computerized familial risk assessment and tailored messages for identifying individuals for targeted cancer prevention strategies and motivating behavior change. METHODS: We conducted a randomized clinical trial in primary care patients aged 35-65 years using Family Healthware, a self-administered, internet-based tool that collects family history for six common diseases including breast cancer, colon cancer, and ovarian cancer, stratifies risk into three tiers, and provides tailored prevention messages. Cancer screening adherence and consultation were measured at baseline and 6-month follow-up. RESULTS: Of 3283 participants, 34% were at strong or moderate risk of at least one of the cancers. Family Healthware identified additional participants for whom earlier screening (colon cancer, 4.4%; breast cancer, women ages: 35-39 years, 9%) or genetic assessment (colon cancer, 2.5%; breast cancer, 10%; and ovarian cancer, 4%) may be indicated. Fewer than half were already adherent with risk-based screening. Screening adherence improved for all risk categories with no difference between intervention and control groups. Consultation with specialists did not differ between groups. CONCLUSION: Family Healthware identified patients for intensified cancer prevention. Engagement of clinicians and patients, integration with clinical decision support, and inclusion of nonfamilial risk factors may be necessary to achieve the full potential of computerized risk assessment.
机译：目的：评估计算机家族性风险评估的有效性和量身定制的信息，以识别有针对性的癌症预防策略和促进行为改变的个体。方法：我们使用家庭保健软件对35-65岁的初级保健患者进行了一项随机临床试验，这是一种自我管理的，基于互联网的工具，该工具收集了包括乳腺癌，结肠癌和卵巢癌在内的六种常见疾病的家族病史。将风险分为三层，并提供量身定制的预防信息。在基线和6个月的随访中测量癌症筛查的依从性和咨询率。结果：在3283名参与者中，有34％处于至少一种癌症的强烈或中度风险。 Family Healthware确定了其他参与者，这些参与者需要进行早期筛查（结肠癌，占4.4％;乳腺癌，女性年龄：35-39岁，占9％）或进行基因评估（结肠癌，占2.5％;乳腺癌，占10％;卵巢癌， 4％）。不到一半的人已经接受了基于风险的筛查。对于所有风险类别，筛查依从性均得到改善，干预组和对照组之间没有差异。各组之间的专家咨询没有差异。结论：家庭保健软件确定了可以加强癌症预防的患者。要充分发挥计算机化风险评估的潜力，可能需要临床医生和患者的参与，与临床决策支持的整合以及非家族性危险因素的纳入。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号