Eosinophil-mediated signalling attenuates inflammatory responses in experimental colitis

Masterson Joanne C.; McNamee Eoin N.; Fillon Sophie A.; Hosford Lindsay; Harris Rachel; Fernando Shahan D.; Jedlicka Paul; Iwamoto Ryo; Jacobsen Elizabeth; Protheroe Cheryl; Eltzschig Holger K.; Colgan Sean P.; Arita Makoto; Lee James J.; Furuta Glenn T.

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Eosinophil-mediated signalling attenuates inflammatory responses in experimental colitis

机译：嗜酸性粒细胞介导的信号减弱实验性结肠炎的炎症反应

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Objective Eosinophils reside in the colonic mucosa and increase significantly during disease. Although a number of studies have suggested that eosinophils contribute to the pathogenesis of GI inflammation, the expanding scope of eosinophil-mediated activities indicate that they also regulate local immune responses and modulate tissue inflammation. We sought to define the impact of eosinophils that respond to acute phases of colitis in mice.

机译：目的嗜酸性粒细胞驻留在结肠粘膜中，并在疾病期间显着增加。尽管许多研究表明，嗜酸性粒细胞促成了胃肠道炎症的发病机理，但嗜酸性粒细胞介导的活性范围的扩大表明它们也调节局部免疫应答并调节组织炎症。我们试图定义对小鼠结肠炎急性期有反应的嗜酸性粒细胞的影响。

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《Gut: Journal of the British Society of Gastroenterology》 |2015年第8期|共12页
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Masterson Joanne C.; McNamee Eoin N.; Fillon Sophie A.; Hosford Lindsay; Harris Rachel; Fernando Shahan D.; Jedlicka Paul; Iwamoto Ryo; Jacobsen Elizabeth; Protheroe Cheryl; Eltzschig Holger K.; Colgan Sean P.; Arita Makoto; Lee James J.; Furuta Glenn T.;
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正文语种 eng
中图分类消化系及腹部疾病;
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1. Eosinophil-mediated signalling attenuates inflammatory responses in experimental colitis [J] . Masterson Joanne C., McNamee Eoin N., Fillon Sophie A., Gut: Journal of the British Society of Gastroenterology . 2015,第8期

机译：嗜酸性粒细胞介导的信号减弱实验性结肠炎的炎症反应
2. Ginsenoside Rd attenuates the inflammatory response via modulating p38 and JNK signaling pathways in rats with TNBS-induced relapsing colitis [J] . YangX.-L., GuoT.-K., WangY.-H., International immunopharmacology . 2012,第2期

机译：人参皂苷Rd通过调节TNBS诱发的复发性结肠炎大鼠的p38和JNK信号转导通路减弱炎症反应
3. Chlorogenic acid ameliorates experimental colitis in mice by suppressing signaling pathways involved in inflammatory response and apoptosis [J] . Iva Vukeli?, Dijana Detel, Lara Bati?i? Pu?ar, Food and Chemical Toxicology: An International Journal Published for the British Industrial Biological Research . 2018,第期

机译：通过抑制炎症反应和细胞凋亡的信号传导途径来改善小鼠的实验性结肠炎
4. A novel therapy for colitis utilizing PPARgamma ligands to inhibit the epithelial inflammatory response [C] . C. G. SU, X. WENG, S. T. BAILEY, Falk Symposium . 2000

机译：一种新的结肠炎利用ppargamma配体抑制上皮炎症反应的新疗法
5. Significance of the wingless-type/beta-catenin signaling cascade for cancer risk in inflammatory bowel disease: Association of genetic polymorphism in human dishevelled 1 with dysplasia in ulcerative colitis. [D] . Uthoff, Sonja Martina Stefanie. 2004

机译：无翼型/β-连环蛋白信号传导级联对于炎症性肠病的癌症风险的意义：人类衣衫不整的1的遗传多态性与溃疡性结肠炎的不典型增生相关。
6. Original article: Eosinophil-mediated signalling attenuates inflammatory responses in experimental colitis [O] . Joanne C Masterson, Eóin N McNamee, Sophie A Fillon, -1

机译：原始文章：嗜酸性粒细胞介导的信号减弱实验性结肠炎的炎症反应
7. Eosinophil-mediated signalling attenuates inflammatory responses in experimental colitis [O] . Joanne C Masterson, Eóin N McNamee, Sophie A Fillon, 2014

机译：嗜酸性粒细胞介导的信号传导衰减实验性结肠炎中的炎症反应
8. Wound Trauma Mediated Inflammatory Signaling Attenuates a Tissue Regenerative Response in MRL/MpJ Mice [R] . Zins, S. R., Amare, M. F., Anam, K., 2010

机译：伤口创伤介导的炎症信号减弱mRL / mpJ小鼠的组织再生反应

Eosinophil-mediated signalling attenuates inflammatory responses in experimental colitis

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