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首页> 外文期刊>Ear, nose and throat journal >Comparison of a microsliced modified chondroperichondrium shield graft and a temporalis fascia graft in primary type I tympanoplasty: A prospective randomized controlled trial
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Comparison of a microsliced modified chondroperichondrium shield graft and a temporalis fascia graft in primary type I tympanoplasty: A prospective randomized controlled trial

机译：Ⅰ型原发性鼓膜成形术中微切面改良软骨软骨膜盾形移植物和颞temporal筋膜移植物的比较：一项前瞻性随机对照试验

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We conducted a prospective, randomized, controlled trial to compare outcomes in type I tympanoplasty patients who received an autologous microsliced modified cartilage perichondrium shield graft (cartilage group) and those who received an autologous temporalis muscle fascia graft (fascia group). Our three outcomes measures were (1) anatomic success rates at 3 months, (2) hearing results at 6 months, and (3) rates of morphologic success (i.e., the absence of reperforation, retraction, and graft displacement) at 2 years among those in each group who had an intact graft at 3 months. Of 56 patients who were initially enrolled and who underwent one of these type I tympanoplasty procedures, 51 completed the study-28 in the cartilage group and 23 in the fascia group. The former was made up of 11 males and 17 females, aged 15 to 48 years (mean: 27.4), and the latter included 9 males and 14 females, aged 15 to 52 years (mean: 31.7). The overall graft take rate at 3 months with respect to perforation closure (anatomic success) was 93.3% in the cartilage group and 91.7% in the fascia group, which was not a statistically significant difference. The mean hearing gain at 6 months was 11.7 +/- 7.6 dB in the cartilage group and 12.6 +/- 6.0 dB in the fascia group-again, not statistically significant. At 2 years, morphologic success rates were 92.3 and 81.0%, respectively-again, not statistically significant. We conclude that autologous microsliced modified cartilage perichondrium shield graft tympanoplasty is as effective as conventional temporalis fascia tympanoplasty in terms of graft take rates and functional results. Indeed, medium-term outcomes (2-yr follow-up) revealed that sustainable morphologic success was actually better with the cartilage technique than with the fascia technique because it was associated with fewer revision surgeries.
机译：我们进行了一项前瞻性，随机对照试验，比较了接受自体微切片改良软骨软骨膜护盾移植物（软骨组）和接受自体颞肌筋膜移植物（筋膜组）的I型鼓室成形术患者的结局。我们的三个结果指标是：（1）3个月时的解剖成功率，（2）6个月时的听力结果，以及（3）2年时的形态学成功率（即无穿孔，无回缩和移植物移位）每组中有3个月完整移植的患者。在最初入组并接受I型鼓膜成形手术之一的56例患者中，有51例完成了这项研究，其中软骨组完成了28项，筋膜组完成了23项。前者由11名男性和17名女性组成，年龄在15至48岁（平均：27.4），而后者包括9名男性和14名女性，年龄在15至52岁之间（平均：31.7）。相对于穿孔闭合（解剖学成功）而言，软骨组在3个月时的总移植物摄取率为93.3％，筋膜组为91.7％，差异无统计学意义。软骨组6个月的平均听力增益为11.7 +/- 7.6 dB，筋膜组为12.6 +/- 6.0 dB，再次无统计学意义。在2年时，形态学成功率再次分别为92.3％和81.0％，无统计学意义。我们得出的结论是，就移植物的取材率和功能效果而言，自体微切片修饰的软骨软骨膜盾构鼓膜成形术与常规颞筋膜鼓膜成形术一样有效。确实，中期结果（2年随访）显示，软骨技术的可持续形态学成功率比筋膜技术要好，因为它与更少的翻修手术相关。

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