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首页> 外文期刊>Graefe's archive for clinical and experimental ophthalmology: Albrecht von Graefes Archiv fur klinische und experimentelle Opthalmologie >One year outcome of manual alcohol-assisted removal of Salzmann's nodular degeneration.
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One year outcome of manual alcohol-assisted removal of Salzmann's nodular degeneration.

机译：人工酒精辅助去除Salzmann结节性变性一年的结果。

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摘要

BACKGROUND: To analyze visual and refractive modifications and corneal topography changes in a patient treated for bilateral advanced Salzmann's nodular degeneration (SND). METHODS: A forty-three-year-old man with bilateral advanced SND underwent manual, alcohol-assisted removal of the altered layer. Visual acuity, refraction, corneal topography and corneal aberrations were examined before and after the treatment after 7 days and 1, 6 and 12 months. RESULTS: The uncorrected visual acuity changed from 0.1 to 1.0 in both eyes. Refraction changed from sphere +3.00 and cylinder +4.50 x 180 degrees in the right eye and sphere +6 and cylinder +4.0 x 170 degrees in the left eye to bilateral emetropia. Corneal topography recovered from an extremely flat profile to a normal shape and it was unvaried during the follow-up period. Main topographic indices, highly altered before the treatment, normalized and were normal at control examinations. The quality of vision improved significantly with reduction of high-order aberrations from RMS of 5,07 microm to 0,66 microm in the right eye and RMS of 4,89 microm to 0,57 microm in the left eye respectively. CONCLUSIONS: Salzmann nodules produce an impressive central corneal flattening with high hyperopic refractive error and significant increment of corneal aberrations. After manual removal of the altered layer, the visual and refractive recovery, corneal topography and aberrometry normalization were immediate and stable during the observational period.
机译：背景：为了分析双侧晚期萨尔兹曼结节性变性（SND）的患者的视力和屈光度改变以及角膜地形变化。方法：一名四十三岁，患有双侧晚期SND的男子接受了酒精辅助的人工去除病变层的手术。在治疗前后7天，1、6和12个月检查视力，屈光度，角膜地形图和角膜像差。结果：两只眼睛的未矫正视力从0.1变为1.0。屈光度从右眼的球面+3.00和柱面+4.50 x 180度，左眼的球面+6和柱面+4.0 x 170度变为双侧屈光不正。角膜地形图从非常平坦的轮廓恢复到正常形状，并且在随访期间没有变化。在治疗前变化很大的主要地形指数正常化，在对照检查中是正常的。通过将高阶像差分别从右眼的5.07微米减小到0.66微米和将左眼的RMS从4.89微米减小到0.57微米，视觉质量得到了显着改善。结论：Salzmann结节产生了令人印象深刻的中央角膜变平，高度远视屈光不正并且角膜像差显着增加。手动去除改变的层后，在观察期内，视觉和屈光恢复，角膜地形图和像差法正常化是即时且稳定的。

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