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The immunocompromised adult patient and surgery

机译:免疫受损的成年患者和手术

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The perioperative management of immunosuppressed patients remains relatively unsophisticated. Rational management involves understanding the normal immune response to injury as modified by the preexisting or imposed abnormalities that immunosuppressed patients manifest on the basis of their disease and/or treatment. Patients with cancer, infected with human immunodeficiency virus, and having had an organ transplant are extreme examples of disordered immunity and it is important to understand the effects of their diseases and treatments. In the future, however, more appropriate management will require anticipation and appreciation of frequent preoperative immunotherapy, a more complete understanding of the immunological response to anesthesia and surgery, the ability to assess immune reserve and stratify risk within the context of that profile, and a better knowledge of the immunological effect of anesthetic agents.
机译:免疫抑制患者的围手术期管理仍然相对复杂。合理的管理包括了解对受伤的正常免疫反应,这种免疫反应是由免疫抑制患者根据其疾病和/或治疗表现出的先前存在或强加的异常而改变的。患有癌症,感染了人类免疫缺陷病毒并进行器官移植的患者是免疫紊乱的极端例子,了解其疾病和治疗的影响非常重要。但是,在未来,更适当的管理将需要对术前频繁进行免疫治疗的预期和赞赏,需要对麻醉和手术的免疫学反应有更全面的了解,在此背景下评估免疫储备和分层风险的能力,以及更好地了解麻醉剂的免疫学作用。

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