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首页> 外文期刊>Best practice & research:Clinical anaesthesiology >Direct markers of organ perfusion to guide fluid therapy: when to start, when to stop.
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Direct markers of organ perfusion to guide fluid therapy: when to start, when to stop.

机译:器官灌注的直接标志物指导液体疗法:何时开始,何时停止。

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摘要

Up until now, the discussion in the literature as to the choice of fluids is almost completely restricted to the composition, with little to no attention paid to the importance of hemodynamic end points to achieve a desired optimal volume. The determination of fluid volume is left to the discretion of the attending physician with only surrogate markers as guidance the initiation and cessation of fluid therapy. In this article, we aim to discuss the available literature on existing clinical and experimental criteria for the initiation and cessation of fluid therapy. Furthermore, we present recent data that have become available after the introduction of direct in?vivo microscopy of the microcirculation at the bedside, and discuss its potential influence on the existing paradigms and controversies in fluid therapy.
机译:迄今为止,文献中关于流体选择的讨论几乎完全限于组成,几乎没有注意血液动力学终点对于获得所需最佳体积的重要性。体液量的确定由主治医师自行决定,仅使用替代标记作为指导开始和停止体液治疗。在本文中,我们旨在讨论有关开始和停止输液治疗的现有临床和实验标准的可用文献。此外,我们介绍了在床旁引入微循环的直接体内显微镜检查后可获得的最新数据,并讨论了其对液体疗法中现有范例和争议的潜在影响。

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