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Skin connective tissue and ageing

机译:皮肤结缔组织和衰老

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摘要

Collagen atrophy is a major factor in skin ageing. A strong correlation exists between skin collagen loss and oestrogen deficiency caused by the menopause. Skin ageing is associated with a progressive increase in extensibility and a reduction in elasticity. With increasing age, the skin also becomes more fragile and susceptible to trauma, leading to more lacerations and bruising. Furthermore, wound healing is impaired in older women. Oestrogen use after the menopause increases collagen content, dermal thickness and elasticity, and it decreases the likelihood of senile dry skin. Large-scale clinical trials are necessary to help make informed recommendations about postmenopausal oestrogen use and its role in preventing skin ageing.
机译:胶原蛋白萎缩是皮肤老化的主要因素。绝经引起的皮肤胶原蛋白损失与雌激素缺乏之间存在很强的相关性。皮肤老化与可扩展性的逐步增加和弹性的降低有关。随着年龄的增长,皮肤也变得更脆弱,更容易受到创伤,导致更多的撕裂伤和瘀伤。此外,老年妇女的伤口愈合受到损害。绝经后使用雌激素会增加胶原蛋白含量,真皮厚度和弹性,并降低老年性干性皮肤的可能性。必须进行大规模的临床试验,才能对绝经后使用雌激素及其在预防皮肤衰老中的作用提供明智的建议。

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