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首页> 外文期刊>Gynecological endocrinology: the official journal of the International Society of Gynecological Endocrinology >Serum orexin-A (OXA) level decreases in polycystic ovarian syndrome
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Serum orexin-A (OXA) level decreases in polycystic ovarian syndrome

机译：多囊卵巢综合征患者血清orexin-A（OXA）水平降低

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Aim: In the current study, we aimed to investigate whether serum orexin-A (OXA) levels are different in polycystic ovary syndrome (PCOS) subjects.Materials and methods: Thirty-six women with PCOS and 40 healthy, age and body mass index-matched controls were included in the prospective cross-sectional study. All subjects underwent venous blood draws during the early follicular phase after overnight fasting. Serum OXA levels were measured with an enzyme immunoassay (EIA). The relationships between the serum OXA levels and the anthropometric and metabolic parameters were also assessed. Results: The serum OXA levels were lower in the women with PCOS compared to the control group. The serum OXA levels were correlated negatively with systolic blood pressure, theFerriman-Gallway score and LH and free testosterone levels.Conclusion: Our results indicate that serum OXA levels decrease in the serum of women with PCOS.
机译：目的：在本研究中，我们旨在调查多囊卵巢综合征（PCOS）受试者的血清orexin-A（OXA）水平是否不同。材料与方法：36例PCOS和40名健康，年龄和体重指数的女性匹配的对照包括在前瞻性横断面研究中。禁食过夜后，在卵泡早期，所有受试者均接受静脉抽血。血清OXA水平用酶免疫法（EIA）测量。还评估了血清OXA水平与人体测量和代谢参数之间的关系。结果：PCOS女性的血清OXA水平低于对照组。血清OXA水平与收缩压，Ferriman-Gallway评分以及LH和游离睾丸激素水平呈负相关。结论：我们的结果表明，PCOS女性血清OXA水平降低。

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