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首页> 外文期刊>Gynecological endocrinology: the official journal of the International Society of Gynecological Endocrinology >Impact of air pollution on fertility: a systematic review
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Impact of air pollution on fertility: a systematic review

机译：空气污染对生育的影响：系统评价

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摘要

Air pollution has gained considerable interest because of the multiple adverse effects reported on human health, although its impact on fertility remains unclear. A systematic search was performed to evaluate the impact of air pollutants on fertility. Controlled trials and observational studies assessing animal model and epidemiological model were included. Occupational exposure and semen quality studies were not considered. Outcomes of interest included live birth, miscarriage, clinical pregnancy, implantation, and embryo quality. Ten studies were included and divided into two groups: animal studies and human epidemiological studies including the general population as well as women undergoing in vitro fertilization and embryo transfer (IVF/ET). Results from this systematic review suggest a significant impact of air pollution on miscarriage and clinical pregnancy rates in the general population, whereas among subfertile patients certain air pollutants seem to exert a greater impact on fertility outcomes, including miscarriage and live birth rates. Besides, studies in mammals observed a clear detrimental effect on fertility outcomes associated to air pollutants at high concentration. The lack of prospective studies evaluating the effect of air pollution exposure in terms of live birth constitutes an important limitation in this review. Thus, further studies are needed to confirm these findings.
机译：空气污染引起了人们极大的兴趣，因为据报道，其对人类健康的多重不利影响，尽管其对生育力的影响尚不清楚。进行了系统的搜索，以评估空气污染物对生育力的影响。包括评估动物模型和流行病学模型的对照试验和观察性研究。没有考虑职业接触和精液质量研究。感兴趣的结果包括活产，流产，临床妊娠，着床和胚胎质量。包括十项研究，分为两组：动物研究和人类流行病学研究，包括普通人群以及接受体外受精和胚胎移植（IVF / ET）的妇女。这项系统评价的结果表明，空气污染对普通人群的流产和临床妊娠率具有重大影响，而在不育患者中，某些空气污染物似乎对生育结局具有更大的影响，包括流产和活产率。此外，在哺乳动物中的研究观察到与高浓度空气污染物相关的生育结局有明显的有害影响。缺乏前瞻性研究来评估空气污染对活产婴儿的影响构成了本综述的重要限制。因此，需要进一步的研究来证实这些发现。

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