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首页> 外文期刊>Gynecological endocrinology: the official journal of the International Society of Gynecological Endocrinology >Neuroendocrine aspects of placenta and pregnancy
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Neuroendocrine aspects of placenta and pregnancy

机译：胎盘和怀孕的神经内分泌方面

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Placenta plays a central role in the regulation of physiological mechanisms of pregnancy, and in particular is the organ of communication between mother and fetus. This action is also related to its ability to produce hormones, growth factors and cytokines during the progression of pregnancy, and in response to stimuli such as stress and inflammation/infection. In the last years the understanding of the physiological and pathological functions of human placenta revealed the hypersecretion of hormones in presence of gestational diseases and raised the question whether this mechanism is cause of disorders of pregnancy, or part of an adaptive response of placenta to resolve adverse conditions. However, there are evidences indicating that changes of placenta! hormone secretion may have clinical usefulness, since they are measurable in biological fluids, and may be used as predictive markers or prognostic tools. Of particular interest is the role of corticotropin releasing hormone, urocortins and activins in the maintaining physiological pregnancy and in the pathogenesis of diseases (preterm birth and preedampsia).
机译：胎盘在调节怀孕的生理机制中起着核心作用，尤其是母亲和胎儿之间的交流器官。该作用还与它在妊娠过程中以及对诸如压力和炎症/感染等刺激的反应中产生激素，生长因子和细胞因子的能力有关。近年来，对人类胎盘生理和病理功能的了解揭示了妊娠疾病存在时激素的过度分泌，并提出了这种机制是否是妊娠疾病的原因，还是胎盘对不良反应的适应性反应的一部分的问题。条件。但是，有证据表明胎盘改变了！激素分泌可能具有临床意义，因为它们可以在生物体液中测量，并且可以用作预测标记或预后工具。特别令人关注的是，促肾上腺皮质激素释放激素，尿皮质素和激活素在维持生理妊娠和疾病（早产和足前充血）的发病机理中的作用。

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