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首页> 外文期刊>Gynecological endocrinology: the official journal of the International Society of Gynecological Endocrinology >Current alternative and complementary therapies used in menopause.
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Current alternative and complementary therapies used in menopause.

机译：目前用于更年期的替代和补充疗法。

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OBJECTIVE: To determine the efficacy and safety of common complementary and alternative medicine (CAM) therapies used to relieve the menopausal symptoms. DESIGN: Comprehensive literature search was conducted through the databases Medline, EMBASE, Cochrane, AMED (Allied and Complementary Medicine), NCCAM (The National Centre for Complementary and Alternative Medicine) to identify relevant monographs in English language. RESULTS: Studies have shown that some therapies such as clonidine, selective serotonin receptor inhibitors (SSRIs) and gabapentin are effective in decreasing the degree and frequency of somatic symptoms in menopause, while phytooestrogens and black cohosh have shown mixed results. Use of Ginseng, evening primrose, Dong Quai or vitamin E appears not to be efficacious for the relieving hot flushes. Other effects of these therapies including possible improvements in mood are yet to be substantiated. INCLUSION CRITERIA: All available human complementary medicine studies on menopausal women with regard to the relief of menopausal symptoms. EXCLUSION CRITERIA: Studies not meeting the inclusion criteria, published in languages other than English or animal studies. CONCLUSION: There is a general lacking of longer-term follow-up beyond the trial lengths of 6-12 weeks in the use of CAM, although women may be taking these medications for many years. Well-designed, randomised control trials are needed to elucidate the true effect of these therapies above the placebo effect.
机译：目的：确定缓解更年期症状的常用补充和替代药物（CAM）疗法的疗效和安全性。设计：通过数据库Medline，EMBASE，Cochrane，AMED（联盟和补充医学），NCCAM（国家补充和替代医学中心）进行全面的文献检索，以识别英语相关的专着。结果：研究表明，可乐定，选择性5-羟色胺受体抑制剂（SSRIs）和加巴喷丁等疗法可有效降低绝经期躯体症状的程度和频率，而植物雌激素和黑升麻则表现出不同的结果。使用人参，月见草，冬葵或维生素E似乎对缓解潮热没有效果。这些疗法的其他效果包括可能改善情绪的效果尚未得到证实。纳入标准：关于绝经症状缓解的所有有关绝经妇女的人类补充医学研究。排除标准：不符合纳入标准的研究，以英语或动物研究以外的其他语言发表。结论：尽管女性可能服用这些药物很多年，但在使用CAM的6-12周的试验期之外，通常缺乏长期随访。需要设计良好的随机对照试验来阐明这些疗法的真实效果高于安慰剂效果。

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