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首页> 外文期刊>Gynecologie, obstetrique & fertilit >Do there still exist risk factors for breast cancer?
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Do there still exist risk factors for breast cancer?

机译:仍然存在乳腺癌的危险因素吗?

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摘要

OBJECTIVES: To evaluate the risk factors associated with a breast cancer, and to compare the proportion of women at high and low risk for developing breast cancer. PATIENTS AND METHODS: Retrospective study among 194 women with breast cancer between January 2007 and December 2008 in the Obstetrics, Gynaecology and Reproductive Medicine department of the Amiens' University hospital. RESULTS: Concerning all the series, only age, overweight and family antecedents seem risk factors of breast cancer. The proportion of women in the low-risk group (12.3%) is not significantly different from that of the high-risk group (18.5%). In the low-risk group, the factors which seem to influence a breast cancer are those in connection with high levels of estrogens (early age of the first menstruation, late age of the menopause and oral contraceptive use) and the smoke habitus; whereas in the high-risk group, the factors are the nulliparity and the absence of breast feeding. DISCUSSION AND CONCLUSIONS: One finds in this series a part only of the known risk factors of breast cancer; and the proportion of women at low risk (12.3%) is comparable with that at high risk (18.5%). This study shows the relative weight of the various risk factors of breast cancer, at a time when its prevalence reached 10%.
机译:目的:评估与乳腺癌相关的危险因素,并比较罹患乳腺癌的高危和低危女性的比例。患者与方法:对亚眠大学附属医院妇产科和生殖医学科2007年1月至2008年12月之间的194名乳腺癌妇女进行回顾性研究。结果:就所有系列而言,只有年龄,超重和家庭先行因素才是乳腺癌的危险因素。低风险组的女性比例(12.3%)与高风险组的女性比例(18.5%)没有显着差异。在低危人群中,似乎影响乳腺癌的因素是与高水平的雌激素有关的因素(第一次月经的早年龄,绝经的晚期和口服避孕药的使用);而在高危人群中,这些因素是无效和没有母乳喂养。讨论与结论:在本系列中,仅发现了一部分已知的乳腺癌危险因素。低风险妇女的比例(12.3%)与高风险妇女的比例(18.5%)相当。这项研究显示,在患病率达到10%时,乳腺癌各种危险因素的相对权重。

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